Hypersil™ PREP HS C8 HPLC Columns

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Industrial Chromatography

Get maximum loading for your scale up from analytical to a prep LC method with Thermo Scientific™ Hypersil™ PREP HS C8 reversed phase preparative HPLC column. With similar selectivity to C18 columns and predictable elution order, C8 columns are ideal for analytes with medium hydrophobicity or when a less hydrophobic phase is required to obtain optimum retention. The lower hydrophobicity allows compounds to elute more quickly, yielding faster separations. By providing high surface area particles with a 100Å pore size, and a variety of dimensions including an option for XtendedLife hardware, which improves column lifetime by maintaining a uniform packed bed.

Catalog number	Product Size	Diameter (Metric)	Length (Metric)	Particle Size
41103-052130	'>Each	'>2 mm	'>50 mm	'>3 µm
41103-054630	'>Each	'>4.6 mm	'>50 mm	'>3 µm
41103-102130	'>Each	'>2 mm	'>100 mm	'>3 µm
41103-104630	'>Each	'>4.6 mm	'>100 mm	'>3 µm
41103-152130	'>Each	'>2 mm	'>150 mm	'>3 µm
41103-154630	'>Each	'>4.6 mm	'>150 mm	'>3 µm
41103-252130	'>Each	'>2 mm	'>250 mm	'>3 µm
41103-254630	'>Each	'>4.6 mm	'>250 mm	'>3 µm
41105-052130	'>Each	'>2 mm	'>50 mm	'>5 µm
41105-054630	'>Each	'>4.6 mm	'>50 mm	'>5 µm
41105-059070A	'>Each	'>10 mm	'>50 mm	'>5 µm
41105-059270A	'>Each	'>20 mm	'>50 mm	'>5 µm
41105-059270XL	'>Each	'>25 mm	'>50 mm	'>5 µm
41105-102130	'>Each	'>2 mm	'>100 mm	'>5 µm
41105-104630	'>Each	'>4.6 mm	'>100 mm	'>5 µm
41105-109070A	'>Each	'>10 mm	'>100 mm	'>5 µm
41105-109270A	'>Each	'>20 mm	'>100 mm	'>5 µm
41105-109270XL	'>Each	'>25 mm	'>100 mm	'>5 µm
41105-152130	'>Each	'>2 mm	'>150 mm	'>5 µm
41105-154630	'>Each	'>4.6 mm	'>150 mm	'>5 µm
41105-159070A	'>Each	'>10 mm	'>150 mm	'>5 µm
41105-159270A	'>Each	'>20 mm	'>150 mm	'>5 µm
41105-159270XL	'>Each	'>25 mm	'>150 mm	'>5 µm
41105-159370A	'>Each	'>30 mm	'>150 mm	'>5 µm
41105-159370XL	'>Each	'>30 mm	'>150 mm	'>5 µm
41105-159570A	'>Each	'>50 mm	'>150 mm	'>5 µm
41105-159570XL	'>Each	'>50 mm	'>150 mm	'>5 µm
41105-252130	'>Each	'>2 mm	'>250 mm	'>5 µm
41105-254630	'>Each	'>4.6 mm	'>250 mm	'>5 µm
41105-259070A	'>Each	'>10 mm	'>250 mm	'>5 µm
41105-259270A	'>Each	'>20 mm	'>250 mm	'>5 µm
41105-259270XL	'>Each	'>25 mm	'>250 mm	'>5 µm
41105-259370A	'>Each	'>30 mm	'>250 mm	'>5 µm
41105-259370XL	'>Each	'>30 mm	'>250 mm	'>5 µm
41105-259570A	'>Each	'>50 mm	'>250 mm	'>5 µm
41105-259570XL	'>Each	'>50 mm	'>250 mm	'>5 µm
41110-018823A	'>Each	'>10 mm	'>8 mm	'>10 µm
41110-019023A	'>Each	'>10 mm	'>20 mm	'>10 µm
41110-019323A	'>Each	'>10 mm	'>30 mm	'>10 µm
41110-019323B	'>Each	'>10 mm	'>30 mm	'>10 µm
41110-029023A	'>Each	'>20 mm	'>20 mm	'>10 µm
41110-029323A	'>Each	'>20 mm	'>30 mm	'>10 µm
41110-029323B	'>Each	'>20 mm	'>30 mm	'>10 µm
41110-059070A	'>Each	'>10 mm	'>50 mm	'>10 µm
41110-059270A	'>Each	'>20 mm	'>50 mm	'>10 µm
41110-059270XL	'>Each	'>25 mm	'>50 mm	'>10 µm
41110-109070A	'>Each	'>10 mm	'>100 mm	'>10 µm
41110-109270A	'>Each	'>20 mm	'>100 mm	'>10 µm
41110-109270XL	'>Each	'>25 mm	'>100 mm	'>10 µm
41110-159070A	'>Each	'>10 mm	'>150 mm	'>10 µm
41110-159270A	'>Each	'>20 mm	'>150 mm	'>10 µm
41110-159270XL	'>Each	'>25 mm	'>150 mm	'>10 µm
41110-159370A	'>Each	'>30 mm	'>150 mm	'>10 µm
41110-159370XL	'>Each	'>30 mm	'>150 mm	'>10 µm
41110-159570A	'>Each	'>50 mm	'>150 mm	'>10 µm
41110-159570XL	'>Each	'>50 mm	'>150 mm	'>10 µm
41110-259070A	'>Each	'>10 mm	'>250 mm	'>10 µm
41110-259270A	'>Each	'>20 mm	'>250 mm	'>10 µm
41110-259270XL	'>Each	'>25 mm	'>250 mm	'>10 µm
41110-259370A	'>Each	'>30 mm	'>250 mm	'>10 µm
41110-259370XL	'>Each	'>30 mm	'>250 mm	'>10 µm
41110-259570A	'>Each	'>50 mm	'>250 mm	'>10 µm
41110-259570XL	'>Each	'>50 mm	'>250 mm	'>10 µm

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Description

Similar selectivity, less retention than C18 columns

Successful retention and separation of moderately hydrophobic analytes.
Ideal for fatty acids, which are too hydrophobic for analysis using C18 columns.
C8 (USP L7) selectivity - high surface area particle with 100Å pore size.
pH stable from 2 to 8.
Maximum temperature of 60°C.

Faster separations

Higher analytical throughput compared to C18 alkyl chain chemistry.
Quicker compound elution due to reduced hydrophobic interactions.

Preparative HPLC Column Hardware Options - based on column inner diameter (i.d.) and column performance needs.

Standard Threaded and Standard Flange Hardware

Designed for standard applications, expertly packed and robustly designed to provide versatile products for routine use.
Standard threaded hardware for column i.d. < 40mm.
Standard flange hardware for column i.d. ≥ 40mm.
Standard hardware can be modified on request to be compatible with SFC.

XtendedLife Hardware

Improves column lifetime by incorporating an internal Dynamic Axial Compression (DAC) system, ensuring the media bed is continuously packed tightly.
Compatible with SFC and is available in dimensions up to 50mm i.d.

Preparative Guards are a proven and cost effective way to extend the lifetime of your prep column. Our preparative guard columns require the use of a preparative guard holder.

Customer Specific Orders

If there is a Thermo Scientific stationary phase you are currently using and would like to obtain in a preparative scale not shown or would like to discuss a specific column dimension, we would be happy to discuss your requirements.
Please contact your local sales representative for Customer Specific Orders.
Custom built columns are not eligible for returns.

Hypersil™ PREP HS C8 HPLC Columns

Industrial Chromatography

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Hypersil™ PREP HS C8 HPLC Columns

Industrial Chromatography

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