The Applied Biosystems® TaqMan® Human Protein Kinase Array is an efficient, easy-to-use micro fluidic card for quantitative gene expression analysis of human protein kinase genes important in drug discovery. This product is designed with TaqMan® Gene Expression Assays arrayed in singletons in 384 wells and is compatible with an upgraded Applied Biosystems 7900HT Fast Real-Time PCR System.
The Human Protein Kinase Array contains assays for 68 human kinases. Fifty-three of the 68 kinases are from receptor protein-tyrosine kinase (RPTK) families: EGFR, InsulinR, PDGFR, VEGFR, FGFR, CCK, NGFR, HGFR, EPHR, AXL, TIE, RYK, DDR, RET, ROS, LTK, ROR and MUSK. The remaining 15 kinases are Ser⁄Thr kinases from the kinase families: CAMKL, IRAK, Lmr, RIPK and STKR. We have also selected assays for 26 classic endogenous, non-kinase genes. These genes are involved in signal transduction and mediate protein-protein interaction, transcriptional regulation, neural development and cell adhesion. This product is sold in packages of 4 cards.
The array is pre-formatted and inventoried, cost-effective, convenient and easy to use without needing expensive robotics. Results are reproducible and consistent across samples, studies, and labs —the same data quality from card-to-card and lot-to-lot — even with different operators.
For Research Use Only. Not for use in diagnostic procedures.