These 96-well plates are pre-configured with the most appropriate TaqMan® Gene Expression Assays for a specific biological process, pathway, or disease state. Each plate contains predefined assays and endogenous controls dried-down in the wells, ready for accurate assessment of an entire gene signature in one simple experiment. The panel of assays in the TaqMan® Array 96-well Human Hedgehog Pathway Plate targets genes from the three members of the vertebrate hedgehog (hh) family: Desert hh, Indian hh, and Sonic hh. Also included are two Patched homologs,Ptc1 and Ptc2; and three homologs of Ci (Cubitus interruptus); Gli1,Gli2 and Gli3. Genes from two cell-cell signaling pathways which commonly function in association with Hedgehog signaling (WNT and TGFB) are also included. Other genes involved in signal transduction of the hedgehog signals (MAPK⁄ERK) as well as genes associated with cell differentiation and regulation of development are included.