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Applied Biosystems™

PrepSEQ™ Express Nucleic Acid Extraction Kit

Catalog number: 4466351
Applied Biosystems™

PrepSEQ™ Express Nucleic Acid Extraction Kit

Catalog number: 4466351
Catalog Number
Unit Size
1 kit
Price (USD)
Your Price:
Catalog NumberUnit SizePrice (USD)AvailabilityQuantity
44663511 kit
Your Price:
Product Overview
Citations & References
Additional Information
The AutoMate Express Nucleic Acid Extraction System is an easy-to-use benchtop instrument that enables hands-free automation of the nucleic acid extraction process for contaminant and impurity testing. The instrument uses the established PrepSEQ nucleic acid extraction chemistry for quantitative recovery of DNA and RNA from diverse samples types, including cell culture, raw material (e.g., serum), and in-process downstream purification samples such as column purification or bulk drug substance (BDS) samples.

Key features of the AutoMate Express Nucleic Acid Extraction System inlcude:
• Time-saving, cost-effective DNA extraction for mycoplasma, MMV, and vesivirus
• Reproducible recovery of DNA from complex samples
• Out-of-the-box automation with prefilled PrepSEQ Express cartridges and ready-to-run protocols
• Closed system minimizes the risk of contamination
• Ideal for in-process testing of contaminants

Three-in-one extraction of cell culture contaminants
The AutoMate Express system can be used to perform nucleic acid extraction of the common contaminants for mammalian cell culture manufacturing (mycoplasmas, MMV, and vesiviruses) (see figure below). Flexible protocols are available to isolate DNA and RNA from a single organism, or a 3-in-1 surveillance panel protocol can simultaneously extract mycoplasma, MMV, and vesivirus nucleic acid from a single sample.

Closed system with walk-away automation
The AutoMate Express system automatically performs all steps for efficient nucleic acid extraction from contaminants in a closed environment. The system uses PrepSEQ Express kits that contain sealed cartridges with extraction reagents and plastics, including tips and sample, lysis, and elution tubes. The workflow has been designed for a completely hands-free operation enabling reproducible extraction efficiencies and reduced time-to-results.

For Research Use Only. Not for use in diagnostic procedures.


Sample Type
Biopharmaceutical Purification Sample, Bulk Drug Substance Sample, Cell Cultures
Final Product Type
Genomic DNA, Total RNA
For Use With (Application)
Real-Time Quantitative PCR (qPCR)
For Use With (Equipment)
7500 Fast System, AutoMate Express™ Nucleic Acid Extraction System
High-throughput Compatibility
Automated Protocols
Isolation Technology
Magnetic Bead
Product Line
Purification Target
Genomic DNA, Total RNA
52 Isolations
Run Time
≤ 1 hr.
Shipping Condition
Room Temperature

Contents & Storage

Contains pre-filled reagent cartridges and plastics to perform extraction of DNA and RNA.

Store at room temperature.