5500xl to 5500xl-W with PC upgrade

Catalog number: 4476694

Applied Biosystems™  Related applications: SOLiD® Next-Generation Sequencing

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This is an optical and computer upgrade kit for the 5500xl Genetic Analyzer for conversion to a 5500xl-W system.

The 5500xl-W Genetic Analyzer helps achieve optimal productivity with a faster workflow, two flexible FlowChips, intuitive user workflows, and project scalability. Faster turn-around times are achieved through the introduction of a non-bead based workflow and increased throughput with a combination of higher colony density and improved optics. The 5500xl-W Genetic Analyzer offers these improvements while maintaining the benefits of the 5500 and 5500xl systems: accuracy, sensitivity, and cost effectiveness. With the 5500xl-W Genetic Analyzer, you are empowered to discover rare genetic events or sub-populations of somatic mutations at an unprecedented pace.

Key Benefits:
• Sequencing right here, right now
• Cost-effective sequencing runs with individually configurable lanes
• Superior low-frequency variant detection for whole-exome sequencing or targeted resequencing
• Reproducibility, reliability, and quality for your RNA applications
• Confidence and uniformity in multiplexing with up to 96 barcodes
• Optimal analysis solutions for streamlined productivity and freedom to operate
• New non-bead based workflow for improved project turnaround and efficiency

When Coverage is Not Enough
Additional sequence coverage fails to compensate for poor accuracy in the detection of rare variants that may hold the key to a better understanding cancer progression, disease penetrance, or drug resistance. With a system accuracy of up to 99.999%, the 5500xl-W Genetic Analyzer enables you to perform 25% less sequencing to detect rare variants than a next-generation sequencing platform with 99.99% system accuracy in order to detect somatic variant present at 1% (Figure 2). The industry-leading accuracy of the 5500xl-W Genetic Analyzer enables detection of significant biological variation for applications like whole genome resequencing, targeted resequencing, and whole transcriptome analysis.

When Flexibility, Speed, and Cost are Crucial
Multidisciplinary translational research programs often require processing of multiple samples across multiple applications like whole exome, RNA-seq, and structural variation. The 5500xl-W Genetic Analyzer provides you the flexibility to configure your sequencing runs to your project and throughput needs (Figure 3). The system’s two configurable microfluidic FlowChips process 6–12 independent samples, and the intelligent barcoding kits multiplex up to hundreds of samples in a single run. Pay-Per-Lane Sequencing (PPL-Seq™) and independent run lanes tailor the system to any project scale. The new non-bead based workflow shaves 1–2 days off project workflows for faster project data delivery. Increased colony density coupled with improved optics provides more data from each lane. With the 5500xl-W Genetic Analyzer, avoid project delays by optimizing your run configurations to attain the lowest cost per sample.

When the Utmost Productivity and Efficiency are Essential
Ease of use, quality control, and speed are integral components of any next-generation sequencing workflow. Co-developed with Hitachi-Hi Technologies, the 5500xl-W Genetic Analyzer's elegant tabletop design (Figure 1) is built off “Six-Sigma" processes to streamline your research. The 5500xl-W Genetic Analyzer delivers streamlined fluidics and a simple, intuitive graphical user interface (GUI) for easy setup and run monitoring. Real-time analysis and 60% smaller data footprints expedite data export and analysis time. Additionally, with embedded sequencing controls and reagent usage tracking, the 5500xl-W Genetic Analyzer empowers you to obtain extremely high-quality and biologically-meaningful data out of every sequencing run.

Take Comprehensive Research to New Heights
The superior accuracy, flexibility, and productivity of the 5500xl-W Genetic Analyzer accelerate comprehensive research. Larger translational medicine initiatives, genome consortiums, and disease-subtype stratification projects with resulting groundbreaking publications are now within your grasp. Catch them all with the 5500xl-W Genetic Analyzer.

A Community of Support
With more than 2,000 field personnel, we have the most extensive network of dedicated Field Application Specialists and Service Engineers to work with you, so that you can feel confident that we will be there when and where you need us most.

This product includes:
Scientific CMOS camera and tube lens assembly
New high efficiency objective lens
Mounting accessories and communication cables
NextIO vCore Express
GPU and RAM upgrades, communication cables
For Research Use Only. Not for use in diagnostic procedures.


Type: System Upgrade, Computer Accessories
Throughput: Up to 120 Gb per run
Read Length: Fragment: 1 x 50 bp
Product Size: 1 each
Input Voltage: 100-240 VAC
Operating System: Linux
For Use With (Equipment): 5500xl Genetic Analyzer, 5500xl W Genetic Analyzer
High Throughput Compatibility: Automated Protocols, High Throughput-Compatible, Multiplexing

Contents & storage

• Scientific CMOS camera and tube lens assembly
• New high efficiency objective lens
• Optics mounting accessories and communication cables
• NextIO vCore Express
• GPU and RAM upgrades, communication cables


Manuals & protocols