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FGFR1 Recombinant Mouse Protein (without Catalytic Activity Domain), hIgG1-Fc Tag

Catalog number: 50186M02H250

 Related applications: Protein Assays and Analysis

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Description

Fibroblast growth factor receptor 1 (FGFR1), recombinant mouse protein is supplied as a lyophilized powder. It is suitable for use in analysis of protein structure. In general, recombinant proteins can also be used as an immunogen, as a protein standard, or in cell biology research applications.

Since this product is a truncated protein and does not contain intracellular catalytic activity domain, it is not suitable for use in enzyme activity studies..

This recombinant protein was expressed from a DNA sequence encoding the extracellular domain (Met 1-Glu 376) of mouse FGFR1 isoform 1 (P16092-1) fused to the Fc region of human IgG1 at the C-terminus.

Activity: Measured by its ability to inhibit FGF1-dependent proliferation of BABL/c 3T3 mouse embryonic fibroblasts. The ED50 for this effect is typically 0.1-0.6 ng/mL.

Formulation: Lyophilized in PBS, pH7.4, 5% Mannitol, 5% Trehalose, and 0.02% Tween-80.

Reconstitution: Dissolve the protein in sterile double distilled water to a concentration of 0.2 mg/ml or lower. It is recommended that the protein be aliquoted and be used as soon as possible. Store aliquots under sterile conditions at -20°C. Avoid repeated freeze-thaw cycles.

Expiration Date: Expires one year from date of receipt when stored as instructed.

This protein is manufactured by SINO Biological.

For Research Use Only. Not for use in diagnostic procedures.

Specifications

Protein Family: Growth Factors & Receptors
Research Category: Cardiovascular Research, Immunology, Neurobiology, Oncology, Signal Transduction, Stem Cell Research
Endotoxin Level: < 1 EU/µg
Expression: Mammalian
Form: Lyophilized
Gene Aliases: AW208770, FLG, Fgfr-1, Flt-2
Gene ID: 14182
Gene Symbol: FGFR1
Kinase Family: FGF Receptor Kinase Family
Molecular Weight: 66.5 kDa
Product Line: Sino Biological®
Product Size: 5 x 50 µg
Protein Form: Recombinant, Truncated
Protein Name: Fibroblast growth factor receptor 1
Protein Subtype: Growth Factor Receptors, Receptor Tyrosine Kinases
Protein Tag or Fusion: IgG1 Fc Tag
Purity: ≥ 85% by SDS-PAGE
Species: Mouse
Validated Application: Assay Standard
Shipping Condition: Room Temperature

Contents & storage

Store at -20 to -70 °C

Documents

Manuals & protocols

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