uTYPE® Dx Allele Library

Catalog number: 53999103

Invitrogen™  Related applications: Diagnostic Testing

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The uTYPE® Dx Allele Library is a master database, provided as a CD, of sequence information for all known human leukocyte antigen (HLA) alleles and variants. It is loaded into the uTYPE® Dx SBT Analysis Software and used to produce in vitro diagnostic HLA typing results from data generated by the 3500 Dx Genetic Analyzer CS2 instruments.

Features include:

• Imported into the uTYPE® Dx SBT Analysis Software
• Available on a subscription basis
• Released quarterly the last week of February, May, August, and November, coinciding with the quarterly update of newly identified HLA alleles
• Used to produce IVD-labeled results

This allele library is imported in the uTYPE® Dx SBT Analysis Software. The software compares data produced by the genetic analyzer to the allele library (variant database) and outputs sample HLA typing results. Typing can be done for the following loci: A, B, C, DRB1, DRB Group, DQB1 and DPB1. It is a required part of the diagnostic HLA workflow. Included in this workflow are the following: SeCore®HLA typing kits, the Veriti® Dx 96-well Thermal Cycler, the 3500 Dx Genetic Analyzer CS2 instruments (8 and 24 capillary), the uTYPE® Dx SBT Analysis Software, and the uTYPE® Dx Allele Library. All Dx components must be used to produce HLA IVD typing results.

The uTYPE® Dx v1.0 HLA Sequence Analysis Software is intended to interpret and match sequencing data generated on the Applied Biosystems® 3500 Dx /3500 xL Dx Genetic Analyzer CS2 with the 3500 Dx Series Data Collection Software using HLA sequencing assay kits to known HLA type sequences.

The SeCore® HLA Sequencing System is intended for the identification and definition of Class I and II Human Leukocyte Antigens (HLA) for use in HLA typing. The SeCore® HLA Sequencing System provides human histocompatibility information of HLA Class I (A, B, and C) and Class II (DPB1, DQB1, and DR) loci using genomic DNA isolated from whole blood specimens.

Contents & storage

One CD. Store at room temperature.


Manuals & protocols