Pharma mini Implant Line

Catalog number: 553-6060

Pharma mini Implant Line

Catalog number: 553-6060
Produce high-quality, injectable drug delivery systems with the Thermo Scientific™ Pharma mini Implant Line. This automated end-to-end solution meets cGMP and FDA requirements. Accurate dosing of pre-blended material enters the extruder, which moves material through a die to produce a filament. A closed-loop filament control system ensures that the implant strand has minimal diameter variability. The strand is cut to the required implant diameter and length. Out-of-specification implants are automatically discarded, assuring 100% quality.
 
Catalog Number
553-6060
Unit Size
Each
Barrel
High performance / pharma grade stainless steel M340
Description
Pharma mini HME base unit
Max. Screw Speed
co- and counter-rotating screws
Price (USD)
Full specifications
Feed Zones1
Max. Temperature280°C
BarrelHigh performance / pharma grade stainless steel M340
Hertz50/60Hz
Screw TypeCo- or counter rotating, pharma grade stainless steel 1.4112 (440 B)
Speed10 to 360 min1
Temperature (Metric) OperatingMax. 280°C with 2 set points
Max. Motor Power400w
DescriptionPharma mini HME base unit
Voltage115V ±10%, 230V ±10%
Max. Torque5 Nm / shaft
Volume (Metric)4ml
Max. Volume4ml
Min. Sample Weight3g
Drive Power400w
Electrical Requirements115V ±10%, 230V ±10% 50/60Hz
Max. Screw Speedco- and counter-rotating screws
Unit SizeEach
Showing 1 of 1
Catalog NumberSpecificationsUnit SizeBarrelDescriptionMax. Screw SpeedPrice (USD)
553-6060Full specifications
EachHigh performance / pharma grade stainless steel M340Pharma mini HME base unitco- and counter-rotating screwsRequest A Quote
Feed Zones1
Max. Temperature280°C
BarrelHigh performance / pharma grade stainless steel M340
Hertz50/60Hz
Screw TypeCo- or counter rotating, pharma grade stainless steel 1.4112 (440 B)
Speed10 to 360 min1
Temperature (Metric) OperatingMax. 280°C with 2 set points
Max. Motor Power400w
DescriptionPharma mini HME base unit
Voltage115V ±10%, 230V ±10%
Max. Torque5 Nm / shaft
Volume (Metric)4ml
Max. Volume4ml
Min. Sample Weight3g
Drive Power400w
Electrical Requirements115V ±10%, 230V ±10% 50/60Hz
Max. Screw Speedco- and counter-rotating screws
Unit SizeEach
Showing 1 of 1
The Pharma mini Implant Line offers a complete solution for developing and producing injectable drug delivery systems. High-quality components and precise automation with integrated Quality Control and documentation assures consistent drug implant manufacturing.

Pharma mini Implant Line advantages
  • Hermetically sealed material container for maximum operator and product safety
  • High accuracy gravimetric feeding (± 0.5%, depending on material)
  • Reproducible and stable extrusion process up to 100 g/h
  • Accurate diameter control adjustable in the range of 0.5mm and 2.0mm; precision of final product is ± 0.005% to 0.05% (depending on physical parameters of the compound used)
  • Exact cutting of implant strand into specified length
  • Automated sorting of in-spec and out-of-spec product for 100% quality assurance
  • Integrated software control system for process monitoring, documentation and displaying all relevant system and process data
  • 21 CFR part 11 compliant Batch Report and Audit Trail
Pharma mini Implant Line components
  • Container with containment valve  
  • Gravimetric feeder with feeder screws and feeder stand
  • Pharma mini HME micro compounder  with co- or counter-rotating screws
  • Filament diameter control and cutting unit with sorting unit
  • PLC with integration of all Pharma mini implant line instruments
  • Chiller unit

Figures

Frequently asked questions (FAQs)

Citations & References