Thermo Scientific™

Pharma 11 Twin-screw Extruder

Catalog number: 5530276
Thermo Scientific™

Pharma 11 Twin-screw Extruder

Catalog number: 5530276

Perform material- and labor-effective extrusion with Thermo Scientific™ Pharma 11 Twin-screw Extruder, which requires only a small amount of active pharmaceutical ingredient, operating at throughput levels as low as 20g/h.

The parallel 11mm twin screws and compact design of the Pharma 11 Twin-screw Extruder is fully scalable with the Thermo Scientific stand-alone pharmaceutical compounding systems. Together, you can obtain process relevant results or even perform small scale production.

If you need a complete extrusion solution, a wide range of accessories are available for the Pharma 11 Twin-screw Extruder, including volumetric and gravimetric feeders, a conveyor belt and a pelletizer.
 

 
Catalog Number
5530276
Unit Size
Each
Description
TSG Conversion Kit For Pharma 11 HME
Price (USD)
Full specifications
DescriptionTSG Conversion Kit For Pharma 11 HME
Unit SizeEach
Catalog Number
Unit Size
Each
Description
Pharma 11 HME; 40:1, 1000rpm
Price (USD)
Full specifications
Feed ZonesPermanent liquid cooled feeding port
Max. Temperature280°C
Heating Zones7 x 5 L/D heat/cool zones, +1 heating zone for die
Width (Metric)50cm
Height (Metric)41cm
Pressure100 bar, safety monitored
Screw Diameter (Metric)11mm
Length (Metric)90cm
Screw Typeco-rotating parallel twin-screw
SpeedVariable speed drive system 10 to 1000rpm
MaterialPharma grade stainless steel Boehler M340
Temperature (Metric) Operating10 °C to 280 °C (with appropriate cooling device)
Throughput20 g/h up to 2.5kg/h
DescriptionPharma 11 HME; 40:1, 1000rpm
Diameter (Metric)11mm
Max. Torque6 Nm per shaft, constant torque, safety monitored
Item DescriptionPharma 11 HME; 40:1, 1000rpm
Weight (Metric)55kg
Max. Screw Speed1000rpm
Unit SizeEach
Catalog Number
Unit Size
Each
Description
Pharma 11 Controlled Cooling 40:1 (Bottom Barrel only)
Price (USD)
Full specifications
DescriptionPharma 11 Controlled Cooling 40:1 (Bottom Barrel only)
Unit SizeEach
Catalog Number
Unit Size
Each
Description
Pharma 11 Volumetric Single Screw Feeder
Price (USD)
Full specifications
DescriptionPharma 11 Volumetric Single Screw Feeder
Unit SizeEach
Catalog Number
Unit Size
Each
Description
Pharma 11 Air Cooled Conveyor
Price (USD)
Full specifications
DescriptionPharma 11 Air Cooled Conveyor
Unit SizeEach
Catalog Number
Unit Size
Each
Description
Pharma 11 Varicut Pelletizer
Price (USD)
Full specifications
DescriptionPharma 11 Varicut Pelletizer
Unit SizeEach
Showing 6 of 6
Catalog NumberSpecificationsUnit SizeDescriptionPrice (USD)
5530276Full specifications
EachTSG Conversion Kit For Pharma 11 HMERequest A Quote
DescriptionTSG Conversion Kit For Pharma 11 HME
Unit SizeEach
553-0020Full specifications
EachPharma 11 HME; 40:1, 1000rpmRequest A Quote
Feed ZonesPermanent liquid cooled feeding port
Max. Temperature280°C
Heating Zones7 x 5 L/D heat/cool zones, +1 heating zone for die
Width (Metric)50cm
Height (Metric)41cm
Pressure100 bar, safety monitored
Screw Diameter (Metric)11mm
Length (Metric)90cm
Screw Typeco-rotating parallel twin-screw
SpeedVariable speed drive system 10 to 1000rpm
MaterialPharma grade stainless steel Boehler M340
Temperature (Metric) Operating10 °C to 280 °C (with appropriate cooling device)
Throughput20 g/h up to 2.5kg/h
DescriptionPharma 11 HME; 40:1, 1000rpm
Diameter (Metric)11mm
Max. Torque6 Nm per shaft, constant torque, safety monitored
Item DescriptionPharma 11 HME; 40:1, 1000rpm
Weight (Metric)55kg
Max. Screw Speed1000rpm
Unit SizeEach
553-0138Full specifications
EachPharma 11 Controlled Cooling 40:1 (Bottom Barrel only)Request A Quote
DescriptionPharma 11 Controlled Cooling 40:1 (Bottom Barrel only)
Unit SizeEach
553-0400Full specifications
EachPharma 11 Volumetric Single Screw FeederRequest A Quote
DescriptionPharma 11 Volumetric Single Screw Feeder
Unit SizeEach
553-0600Full specifications
EachPharma 11 Air Cooled ConveyorRequest A Quote
DescriptionPharma 11 Air Cooled Conveyor
Unit SizeEach
553-0610Full specifications
EachPharma 11 Varicut PelletizerRequest A Quote
DescriptionPharma 11 Varicut Pelletizer
Unit SizeEach
Showing 6 of 6

The Pharma 11 Twin-screw Extruder Features:

  • Uses smaller material quantities for faster, cost-effective development
  • Converts easily from hot melt extrusion (HME) to twin screw granulation (TSG) applications
  • Operates at throughput ranges from 20g/h up to 2.5kg/h
  • Processing length: L/D ratio 40:1
  • Screw elements and barrel design scale geometrically across the all Thermo Scientific Pharma Extruders and allow easy process scale-up
  • Easy-to-operate with user-friendly, intuitive touch screen with integrated feeder control
  • Maximize lab space with small footprint machine
  • Perfect for glove box or isolator applications with removable touch screen
  • All material contact parts are easily removable
  • Documentation of extrusion parameters and suitable for process analytical technology (PAT)
  • GMP-compliant, full validation available: FAT, SAT, IQ/OQ

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Frequently asked questions (FAQs)

Citations & References