Search Thermo Fisher Scientific
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Catalog Number | Volume (Metric) |
---|---|
5943462005 | 5 mL |
5943462001 | 1 mL |
CaptureSelect CH1-XL MiniChrom™ columns are designed for bench-scale resin screening, process development, and sample preparation.
These pre-packed columns are ready to connect and have the following features:
The 1 mL columns can be used for quick screenings of application feasibility and lab scale purification on a convenient and easy-to-use pre-packed column. The 10 cm bed height of the 5 mL columns allows initial process development on a bench scale.
The CaptureSelect CH1-XL Affinity Matrix recognizes the CH1 domain of human IgG antibodies, thereby enabling purification of all Fab fragments, independent of the light-chain type (kappa or lambda) and without binding of over-expressed light chain and light-chain dimers. In addition, it can be used for the purification of human IgGs from all four subclasses (1, 2, 3, and 4).
Features of this affinity matrix include:
Free of animal components
CaptureSelect products contain affinity ligands based on recombinant single-domain antibody fragments (VHH) created by a proprietary technology. The VHH affinity ligand is a 12 to 15 kDa fragment comprising the three complementarity-determining regions (CDRs) that form the antigen-binding domain, efficiently produced in the yeast Saccharomyces cerevisiae by a production process free of any animal components (Animal Origin-Free).
Main characteristics: