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Proteintech
NAPSA Monoclonal Antibody (1H7F2)
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Product Details
60259-2-IG
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
1H7F2
Immunogen
NAPSA Fusion Protein Ag9721 (1-420 aa encoded by BC017842)
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein G
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MSPPPLLQP LLLLLPLLNV EPSGATLIRI PLHRVQPGRR TLNLLRGWRE PAELPKLGAP SPGDKPIFVP LSNYRDVQYF GEIGLGTPPQ NFTVAFDTGS SNLWVPSRRC HFFSVPCWLH HRFDPKASSS FQANGTKFAI QYGTGRVDGI LSEDKLTIGG IKGASVIFGE ALWEPSLVFA FAHFDGILGL GFPILSVEGV RPPMDVLVEQ GLLDKPVFSF YLNRDPEEPD GGELVLGGSD PAHYIPPLTF VPVTVPAYWQ IHMERVKVGP GLTLCAKGCA AILDTGTSLI TGPTEEIRAL HAAIGGIPLL AGEYIILCSE IPKLPAVSFL LGGVWFNLTA HDYVIQTTRN GVRLCLSGFQ ALDVPPPAGP FWILGDVFLG TYVAVFDRGD MKSSARVGLA RARTRGADLG WGETAQAQFP G (1-420 aa encoded by BC017842)
Target Information
Napsin 1 is an aspartic protease that is generally expressed in the lung, but also present in kidney and in metastatic carcinomas throughout the body. Napsin 1 processes surfactant protein B in healthy pulmonary and renal tissues, but is abnormally regulated when carcinogenesis occurs. Thus, many researchers have found napsin evaluation to be useful in identifying several cancers, and differentiating primary tumors from metastases. When combined with thyroid transcription factor analysis, napsin can be used as a specific biomarker for differentiation of carcinoma types. Napsin has also been associated with pulmonary alveolar proteinosis as well as in protein catabolism in renal tubules.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: asp 4; ASP4; aspartic proteinase; Aspartyl protease 4; kidney-derived aspartic protease-like protein; Napsin-1; Napsin-A; NR1H2 antisense RNA 1; pronapsin A; TA01/TA02
Gene Aliases: KAP; Kdap; NAP1; NAPA; NAPSA; NR1H2-AS1; SNAPA
UniProt ID: (Human) O96009
Entrez Gene ID: (Human) 9476
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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