Search

  • Order Status
  • Quick Order
  • Promos

Proteintech

ERCC1 Monoclonal Antibody (1H4D5)

1 Reference
View all (93) ERCC1 antibodies

{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}

{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}

{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}

Datasheet
Certificates
Protocols
Questions & Answers
Tech Support
Datasheet
Certificates
Protocols
Questions & Answers
Tech Support
Datasheet
Certificates
Protocols
Questions & Answers
Tech Support
Additional Information:
{{banner.description}}
{{$ctrl.isSkuNotesCollapsed ? 'View more' : 'View less'}}

Product Details

66275-1-IG

Applications
Tested Dilution
Publications

Western Blot (WB)

1:1,000-1:4,000
View 1 publication 1 publication

Immunocytochemistry (ICC/IF)

1:50-1:500
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

1H4D5

Immunogen

ERCC1 Fusion Protein Ag6417 (1-323 aa encoded by BC052813)

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Amount

150 µg

Purification

Protein G

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: MDPGKDKEG VPQPSGPPAR KKFVIPLDED EVPPGVAKPL FRSTQSLPTV DTSAQAAPQT YAEYAISQPL EGAGATCPTG SEPLAGETPN QALKPGAKSN SIIVSPRQRG NPVLKFVRNV PWEFGDVIPD YVLGQSTCAL FLSLRYHNLH PDYIHGRLQS LGKNFALRVL LVQVDVKDPQ QALKELAKMC ILADCTLILA WSPEEAGRYL ETYKAYEQKP ADLLMEKLEQ DFVSRVTECL TTVKSVNKTD SQTLLTTFGS LEQLIAASRE DLALCPGLGP QKVRALGKNP RSWGKERAPN KHNLRPQSFK VKKEPKTRHS GFRL (1-323 aa encoded by BC052813)

Target Information

ERCC1 is a non-catalytic component of a structure-specific DNA repair endonuclease responsible for the 5'-incision during DNA repair. It is responsible, in conjunction with SLX4, for the first step in the repair of interstrand cross-links (ICL). It participates in the processing of anaphase bridge-generating DNA structures, which consist in incompletely processed DNA lesions arising during S or G2 phase, and can result in cytokinesis failure. ERCC1 is also required for homology-directed repair (HDR) of DNA double-strand breaks, in conjunction with SLX4. (Uniprot)

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Bioinformatics

Protein Aliases: clone 2B3; DNA excision repair protein ERCC-1; excision repair cross-complementation group 1; excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence); unnamed protein product

View more View less

Gene Aliases: COFS4; ERCC1; RAD10; UV20

View more View less

UniProt ID: (Human) P07992

View more View less

Entrez Gene ID: (Human) 2067

View more View less

guarantee_icon

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

Learn more
help_icon

We're here to help

Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.

Contact tech support