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Proteintech

Gelsolin Monoclonal Antibody (3C4A2)

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Gelsolin Monoclonal Antibody (3C4A2)

Product Details

66280-1-IG

Applications
Tested Dilution
Publications

Western Blot (WB)

1:1,000-1:4,000
-

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:1,000
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgA

Class

Monoclonal

Type

Antibody

Clone

3C4A2

Immunogen

Gelsolin Fusion Protein Ag17916 (433-782 aa encoded by BC026033)
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: MAAQHGMDD DGTGQKQIWR IEGSNKVPVD PATYGQFYGG DSYIILYNYR HGGRQGQIIY NWQGAQSTQD EVAASAILTA QLDEELGGTP VQSRVVQGKE PAHLMSLFGG KPMIIYKGGT SREGGQTAPA STRLFQVRAN SAGATRAVEV LPKAGALNSN DAFVLKTPSA AYLWVGTGAS EAEKTGAQEL LRVLRAQPVQ VAEGSEPDGF WEALGGKAAY RTSPRLKDKK MDAHPPRLFA CSNKIGRFVI EEVPGELMQE DLATDDVMLL DTWDQVFVWV GKDSQEEEKT EALTSAKRYI ETDPANRDRR TPITVVKQGF EPPSFVGWFL GWDDDYWSVD PLDRAMAELA A (433-782 aa encoded by BC026033)

Target Information

The protein encoded by this gene binds to the "plus" ends of actin monomers and filaments to prevent monomer exchange. The encoded calcium-regulated protein functions in both assembly and disassembly of actin filaments. Defects in this gene are a cause of familial amyloidosis Finnish type (FAF). Multiple transcript variants encoding several different isoforms have been found for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: Actin-depolymerizing factor; ADF; ADFBrevin; AGEL; Brevin; DKFZp313L0718; epididymis secretory sperm binding protein; Gelsolin; RP11-477J21.1; unnamed protein product

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Gene Aliases: ADF; AGEL; AMYLD4; GSN

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UniProt ID: (Human) P06396

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Entrez Gene ID: (Human) 2934

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Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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