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Proteintech
VDAC2 Monoclonal Antibody (1D8C11)
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Product Details
66388-1-IG
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human,
Mouse
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
1D8C11
Immunogen
Peptide
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
150 µg
Purification
Protein G
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Target Information
This gene encodes a member of the voltage-dependent anion channel pore-forming family of proteins that are considered the main pathway for metabolite diffusion across the mitochondrial outer membrane. The encoded protein is also thought to be involved in the mitochondrial apoptotic pathway via regulation of BCL2-antagonist/killer 1 protein activity. Pseudogenes have been identified on chromosomes 1, 2, 12 and 21, and alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: B36-VDAC; epididymis secretory sperm binding protein; FLJ23841; Non-selective voltage-gated ion channel VDAC2; Outer mitochondrial membrane protein porin 2; RP11-375G3.1; unnamed protein product; VDAC-2; VDAC-6; VDAC2; voltage-dependent anion-selective channel protein 2; Voltage-dependent anion-selective channel protein 6
Gene Aliases: mVDAC2; mVDAC6; POR; VDAC2; Vdac6
UniProt ID: (Human) P45880, (Mouse) Q60930, (Rat) P81155
Entrez Gene ID: (Human) 7417, (Mouse) 22334, (Rat) 83531
ion transport
anion transport
lipid transport
binding of sperm to zona pellucida
phospholipid scrambling
phospholipid translocation
transmembrane transport
mitochondrial outer membrane permeabilization
anion transmembrane transport
mitochondrial transmembrane transport
transport
negative regulation of protein polymerization
regulation of anion transport
negative regulation of intrinsic apoptotic signaling pathway
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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