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Proteintech
AQP1 Monoclonal Antibody (2E5D6)
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Product Details
66805-1-IG
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Pig
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
2E5D6
Immunogen
AQP1 Fusion Protein Ag14093 (220-269 aa encoded by BC022486)
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
150 µg
Purification
Protein G
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: GALAVLIYD FILAPRSSDL TDRVKVWTSG QVEEYDLDAD DINSRVEMKP K (220-269 aa encoded by BC022486)
Target Information
Aquaporin 1 is a 28kD integral membrane protein which was originally identified in red blood cells and renal proximal tubules. AQP1 is also expressed by the choroid plexus and various other tissues. It forms a water-specific channel that provides the plasma membranes of red cells and kidney proximal tubules with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 28 kda erythrocyte integral membrane protein homolog; AQP 1; AQP CHIP; AQP-1; aquaporin 1 (channel-forming integral protein, 28kDa, CO blood group); aquaporin 1, Colton blood group antigen; Aquaporin CHIP; Aquaporin-1; Aquaporin-CHIP; Aquaporin1; bloodgroup CO protein; Channel-like integral membrane protein of 28 kDa; channel-like integral membrane protein, 28-kDa; CHIP 28; Colton blood group; Colton blood group antigen; membrane channel; MGC26324; unnamed protein product; Urine water channel; water channel protein for red blood cells and kidney proximal tubule
Gene Aliases: AQP-CHIP; AQP1; CHIP28; CO
UniProt ID: (Pig) Q6PQZ1, (Human) P29972
Entrez Gene ID: (Pig) 407773, (Human) 358
intracellular cGMP activated cation channel activity
potassium channel activity
water transmembrane transporter activity
ammonium transmembrane transporter activity
glycerol transmembrane transporter activity
water channel activity
transmembrane transporter activity
nitric oxide transmembrane transporter activity
carbon dioxide transmembrane transporter activity
protein binding
potassium ion transmembrane transporter activity
channel activity
identical protein binding
ephrin receptor binding
hydrogen peroxide channel activity
transporter
renal water transport
water transport
cell volume homeostasis
cellular water homeostasis
carbon dioxide transport
ammonium transport
glycerol transport
cellular homeostasis
cGMP-mediated signaling
lateral ventricle development
nitric oxide transport
establishment or maintenance of actin cytoskeleton polarity
cellular response to UV
transepithelial water transport
carbon dioxide transmembrane transport
response to drug
negative regulation of apoptotic process
positive regulation of angiogenesis
positive regulation of saliva secretion
positive regulation of fibroblast proliferation
cellular response to hydrogen peroxide
cellular response to inorganic substance
cellular response to mechanical stimulus
cellular response to copper ion
cellular response to mercury ion
cellular response to retinoic acid
cellular response to cAMP
cellular response to hypoxia
cellular response to salt stress
cellular hyperosmotic response
cellular response to dexamethasone stimulus
potassium ion transmembrane transport
ammonium transmembrane transport
maintenance of symbiont-containing vacuole by host
renal water homeostasis
glomerular filtration
potassium ion transport
hyperosmotic response
fibroblast migration
positive regulation of fibroblast migration
cell migration
sensory perception of pain
pancreatic juice secretion
secretion by cell
cerebrospinal fluid secretion
secretory granule organization
wound healing
odontogenesis
lipid digestion
camera-type eye morphogenesis
defense response to Gram-negative bacterium
multicellular organismal water homeostasis
corticotropin secretion
establishment of localization in cell
transmembrane transport
renal water absorption
cellular response to nitric oxide
metanephric descending thin limb development
metanephric proximal straight tubule development
metanephric proximal convoluted tubule segment 2 development
metanephric glomerulus vasculature development
hydrogen peroxide transmembrane transport
cation transmembrane transport
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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