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Proteintech
ATP6V1B2 Monoclonal Antibody (3C11A9)
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FIGURE: 1 / 4
ATP6V1B2 Antibody (68441-1-IG) in WB
Various lysates were subjected to SDS PAGE followed by western blot with 68441-1-Ig (ATP6V1B2 antibody) at dilution of 1:20,000 incubated at room temperature for 1.5 hours. The membrane was stripped and reblotted with HRP-conjugated GAPDH Monoclonal antibody (HRP-60004) as loading control.
Product Details
68441-1-IG
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Pig,
Rabbit,
Rat
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
3C11A9
Immunogen
ATP6V1B2 fusion protein Ag7265
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
150 µg
Purification
Protein G
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: CRIYPEEMIQ TGISAIDGMN SIARGQKIPI FSAAGLPHNE IAAQICRQAG LVKKSKDVVD YSEENFAIVF AAMGVNMETA RFFKSDFEEN GSMDNVCLFL NLANDPTIER IITPRLALTT AEFLAYQCEK HVLVILTDMS SYAEALREVS AAREEVPGRR GFPGYMYTDL ATIYERAGRV EGRNGSITQI PILTMPNDDI THPIPDLTGY ITEGQIYVDR QLHNRQIYPP INVLPSLSRL MKSAIGEGMT RKDHADVSNQ LYACYAIGKD VQAMKAVVGE EALTSDDLLY LEFLQKFERN FIAQGPYENR TVFETLDIGW QLLRIFPKEM LKRIPQSTLS EFYPRDSAKH
Target Information
ATP6V1B2 encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A, three B, and two G subunits, as well as a C, D, E, F, and H subunit. The V1 domain contains the ATP catalytic site. The protein encoded by this gene is one of two V1 domain B subunit isoforms and is the only B isoform highly expressed in osteoclasts.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ATPase, H+ transporting, lysosomal (vacuolar proton pump), beta 56/58 kDa, isoform 2; ATPase, H+ transporting, lysosomal 56/58kD, V1 subunit B, isoform 2; ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1; ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2; ATPase, H+ transporting, V1 subunit B, isoform 2; Endomembrane proton pump 58 kDa subunit; H+ transporting two-sector ATPase; HO57; lysosomal 56/58kDa; testicular secretory protein Li 65; unnamed protein product; V-ATPase B2 subunit; V-ATPase subunit B 2; V-type proton ATPase subunit B, brain isoform; vacuolar H+-ATPase 56,000 subunit; vacuolar H+ATPase B2; Vacuolar proton pump subunit B 2
Gene Aliases: AI194269; AI790362; ATP6B1B2; ATP6B2; ATP6V1B2; DOOD; HO57; R74844; Vat2; VATB; Vma2; VPP3; ZLS2
UniProt ID: (Human) P21281, (Mouse) P62814, (Rat) P62815
Entrez Gene ID: (Human) 526, (Rabbit) 100341367, (Pig) 106504095, (Mouse) 11966, (Rat) 117596
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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