CaptureSelect Biotin Anti-AAVX Conjugate consists of a 14 kDa camelid antibody fragment (affinity ligand) that specifically binds with high affinity and selectivity to native and recombinant adeno-associated virus (AAV) particles of various serotypes. The anti-AAVX affinity ligand has demonstrated binding reactivity towards a large set of different AAV serotypes including AAV1 to AAV8, and AAVrh10, indicating that an even broader range of AAV serotypes could potentially be recognized and detected. The affinity ligand is chemically conjugated to biotin via a spacer that retains the binding reactivity of the ligand when used in combination with streptavidin-based conjugates or streptavidin pre-coated surfaces.
This conjugate enables the detection, quantitation, and characterization of native and recombinant AAV virus particles. Applications for CaptureSelect Biotin Anti-AAVX Conjugate include ELISA, immunoprecipitation with streptavidin-coupled Dynabeads, Gyrolab™-based immunoassays, and use with label-free detection platforms such as those based on surface plasmon resonance (Biacore™ and IBIS-MX96 systems) and bio-layer interferometry (ForteBio™ Octet™ systems).
For Research Use Only. Not for use in diagnostic procedures.