BRD7 Antibody

Catalog number: 730073

Invitrogen™  Related applications: Protein Assays and Analysis | Protein Purification & Isolation

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Description

BRD7 acts both as coactivator and as corepressor. For example, it activates the Wnt signaling pathway in a DVL1-dependent manner by negatively regulating the GSK3B phosphotransferase activity. In addition, it is required for TP53-mediated cell-cycle arrest in response to oncogene activation. BRD7 promotes acetylation of TP53 at Lys-382, and thereby promotes efficient recruitment of TP53 to target promoters, inhibiting cell cycle progression from G1 to S phase.
For Research Use Only. Not for use in diagnostic procedures.

Specifications

Reactivity: Human
Validated Application: Immunoprecipitation
Host Species: Mouse
SubClass (Isotype): IgG1
Clonality: Monoclonal
Antibody Fragment: Whole Antibody
Target Gene: Bromodomain-containing protein 7
Gene ID: 29117
Gene Symbol: BRD7
Accession Number: Q9NPI1
Gene Aliases: BP75, CELTIX1
Label or Dye: Unconjugated
Concentration: 0.5 mg⁄ml
Form: Liquid
Product Size: 100 µg
Buffer: Phosphate buffered saline (PBS) with 0.09% sodium azide.
Research Category: Immunology
Other Additives: Sodium Azide Preservative

Contents & storage

2 - 8 °C for up to 1 month, -20 °C for long storage.

Avoid repeated freezing and thawing.

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