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7TM Antibodies
Phospho-Tachykinin Receptor 2 (Ser345, Thr346) Polyclonal Antibody
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FIGURE: 1 / 1
Phospho-Tachykinin Receptor 2 (Ser345, Thr346) Antibody (7TM0361B) in WB
Agonist-induced Serine345/Threonine346 phosphorylation of NK2 Receptor. Upper panel, HEK293 cells stably expressing the NK2-Receptor (NK2) were either not exposed or exposed to 1 µM of specific NK2-Receptor Agonist Neurokinin B for 30 minutes. Cells were lysed and immunoblotted with the anti-pS345/pT346-NK2 antibody (7TM0361B) at a dilution of 1:1,000. Lower panel, blot was stripped and reprobed with an pho... View More
Product Details
7TM0361B
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic phosphopeptide derived from human NK2 around the phosphorylation site Ser345/Thr346.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
Dulbecco's PBS, pH 7.4
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
This gene belongs to a family of genes that function as receptors for tachykinins. Receptor affinities are specified by variations in the 5'-end of the sequence. The receptors belonging to this family are characterized by interactions with G proteins and 7 hydrophobic transmembrane regions. This gene encodes the receptor for the tachykinin neuropeptide substance K, also referred to as neurokinin A.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: G-protein coupled receptor; TACR2; neurokinin 2 receptor; Neurokinin A receptor; neurokinin B receptor; NK-2 receptor; NK-2R; NK2; seven transmembrane helix receptor; SK receptor; SKR; Substance-K receptor; Tachykinin receptor 2; unnamed protein product
Gene Aliases: NK2R; NKNAR; SKR; TAC2R; TACR2
UniProt ID: (Human) P21452
Entrez Gene ID: (Human) 6865
muscle contraction
regulation of smooth muscle contraction
signal transduction
G-protein coupled receptor signaling pathway
tachykinin receptor signaling pathway
positive regulation of acetylcholine secretion, neurotransmission
intestine smooth muscle contraction
negative regulation of luteinizing hormone secretion
operant conditioning
positive regulation of vascular permeability
positive regulation of ion transport
positive regulation of smooth muscle contraction
response to electrical stimulus
prolactin secretion
regulation of uterine smooth muscle contraction
positive regulation of uterine smooth muscle contraction
positive regulation of sperm motility
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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