Thermo Scientific Pierce 0.1% Trifluoroacetic Acid (v/v) in Acetonitrile, LC-MS Grade is a preparation with high purity and low UV-absorptivity that is ideal for HPLC and mass spectrometry applications.
Features of 0.1% Trifluoroacetic Acid (v/v) in Acetonitrile, LC-MS Grade:
• Validated—tested more than 20 ways to ensure maximal LC-MS sensitivity
• Purified—processed, filtered and sealed to extend LC-MS column life
• Convenient—packaged to eliminate variability and reduce handling
0.1% Trifluoroacetic Acid (TFA) in Acetonitrile is specially purified by a proprietary method and tested to ensure lot-to-lot consistency with a low UV absorbance, providing the most sensitive detection across wavelengths and prolonging equipment life. The chromatography- and spectrometry-grade 0.1% TFA in acetonitrile is 0.2-micron filtered, packaged in solvent-rinsed amber glass bottles and sealed under a nitrogen with PTFE-lined fluorocarbon caps for ultimate protection.
For complex separations, the key to success can be to vary selectivity. Varying mobile phase composition on the same column can change selectivity enough to resolve separations that would otherwise overlap. TFA is the most frequently used modifier for separations in reverse-phase HPLC. The usual specified TFA concentration is 0.1%. For reproducible separations from run-to-run or from lab-to-lab, it is essential to make TFA concentrations the same.
For Research Use Only. Not for use in diagnostic procedures.