Axiom Genome-Wide Population-Optimized Human Arrays are genotyping panels that offer the best genetic coverage of rare and common variants for genome-wide disease association studies.

The Axiom Genome-Wide ASI 1 Array Plate is the first array designed to maximize genomic coverage of rare alleles (MAF >1%) of a consensus East Asian (JPT+CHB) genome

Benefits of Axiom Genome-Wide Population-Optimized Arrays
Each array plate was designed to achieve ˜90% genomic coverage (r² >0.8) in each target population, while covering markers with MAF of 1-5% in areas such as:
• Critical biological categories (e.g., coding SNPs)
• Biological processes (e.g., drug metabolizing genes)
• Disease categories (e.g., cardiovascular disease, cancer, immunity/inflammation, MHC, and CNS)
• Common and rare SNPs and insertions/deletions (indels) from the International HapMap Project, 1000 Genomes Project, and published disease associations
• Genotype-tested genomic content proven to give informative and reliable results
• Markers preselected for coverage in critical biological categories, such as coding SNPs, and biological pathways, such as drug metabolizing or cardiovascular genes
• High sample pass rate, call rate, and reproducibility
• Compatible with the Axiom 2.0 Reagent Kit, GeneTitan™ MC Instrument, automated or manual workflow, and Genotyping Console™ Software

Other Maximum Genome-Wide Coverage Arrays
These array plates are designed to maximize whole-genome coverage of common and rare alleles, including SNPs within 10 kb of genes.
• Axiom Genome-Wide CEU 1 Array Plate - The first cost-effective array to maximize coverage of rare variants (MAF >1%) for European populations
• The Axiom Genome-Wide CHB 1 and CHB 2 Array Set Bundle - This set bundle contains the Axiom Genome-Wide CHB 1 Array Plate and the Axiom Genome-Wide CHB 2 Array Plate. The Axiom Genome-Wide CHB 1 Array Plate maximizes genomic coverage of common alleles (MAF >5%) of the Han Chinese genome. The Axiom Genome-Wide CHB 2 Array Plate is designed to target rare variants (MAF 2-5%) as a complement to Axiom Genome-Wide CHB 1 Array Plate
• The Axiom Genome-Wide CHB 2 Array Plate - This array is designed to target rare variants (MAF 2-5%) as a complement to Axiom Genome-Wide CHB 1 Array Plate. The Axiom Genome-Wide CHB 1 and CHB 2 Array Set Bundle enables the most comprehensive commercially available genome-wide coverage in CHB populations.

• The Axiom Genome-Wide PanAFR Array Plate Set - The first array to offer pan-African genomic coverage, with ≥90% genetic coverage of common and rare variants (MAF >2%) of the Yoruba (West African) genome and >85% coverage of common and rare variants (MAF >2%) of the Luhya and Maasi (East African) genomes. This array set also offers high genomic coverage (>85%) in admixed populations with West African ancestry.

Please visit our NetAffx Analysis Center for more information on microarray analysis

Don't see what you're looking for? Learn how to create an Axiom myDesign™ Array Plate tailored for your study.

Required Products
Axiom Analysis Suite
GeneChip Command Console Software
GeneTitan Multi-Channel Instrument