2-Bromoethanol is utilized in selective reduction of nitroarenes. It is used as a solvent and organic synthetic raw material. It finds application in the synthesis of 2-piperidin-1-yl-ethanol by reacting with piperidine. It is used in selective reduction of nitroarenes.
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Applications
2-Bromoethanol is utilized in selective reduction of nitroarenes. It is used as a solvent and organic synthetic raw material. It finds application in the synthesis of 2-piperidin-1-yl-ethanol by reacting with piperidine. It is used in selective reduction of nitroarenes.
Solubility
Miscible with water, organic solvent and petroleum ether.
Notes
Light sensitive. Hygroscopic. Store in a cool place. Incompatible with strong acids, strong oxidizing agents, strong reducing agents, acid chlorides and acid anhydrides.
RUO – Research Use Only
Carboxylic acids protected as their 2-bromoethyl esters are readily deprotected by cleavage with sodium trithiocarbonate: Synthesis, 715 (1974). 2-Bromoethyl esters of amino acids have been cleaved by conversion with NaI (Finkelstein) to the corresponding iodo esters, followed by reductive cleavage with Zn in DMF: Chem. Ber., 112, 2145 (1979); Angew. Chem. Int. Ed., 20, 894 (1981). See also Appendix 6.
Bao, J.; Tranmer, G. K. The utilization of copper flow reactors in organic synthesis. Chem. Commun. 2015, 51 (15), 3037-3044.
Davis, O. A.; Croft, R. A.; Bull, J. A. Synthesis of diversely functionalised 2, 2-disubstituted oxetanes: fragment motifs in new chemical space. Chem. Commun. 2015, 51 (84), 15446-15449.