1,2,4-Trimethoxybenzene, 98%
1,2,4-Trimethoxybenzene, 98%
1,2,4-Trimethoxybenzene, 98%
1,2,4-Trimethoxybenzene, 98%
Thermo Scientific Chemicals

1,2,4-Trimethoxybenzene, 98%

CAS: 135-77-3 | C9H12O3 | 168.192 g/mol
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Catalog number A10483.09
also known as A10483-09
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Chemical Identifiers
CAS135-77-3
IUPAC Name1,2,4-trimethoxybenzene
Molecular FormulaC9H12O3
InChI KeyAGIQIOSHSMJYJP-UHFFFAOYSA-N
SMILESCOC1=CC=C(OC)C(OC)=C1
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SpecificationsSpecification SheetSpecification Sheet
Appearance (Color)Clear colorless to pale yellow or orange
FormLiquid
Assay (GC)≥97.5%
Identification (FTIR)Conforms
Refractive Index1.5310-1.5350 @ 20°C
1,2,4-Trimethoxybenzene is used as pharmaceutical intermediates.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
1,2,4-Trimethoxybenzene is used as pharmaceutical intermediates.

Solubility
Not miscible in water.

Notes
Store away from incompatible materials such as oxidizing agents, acids and bases. Use only in a chemical fumehood.
RUO – Research Use Only

General References:

  1. Sheryl A. Tucker; Hardjanti Darmodjo; William E. Acree; Maximilian Zander; Erich C. Meister; Mary J. Tanga; and Sumio Tokita. Polycyclic Aromatic Nitrogen Heterocycles. Part IV: Effect of Solvent Polarity, Solvent Acidity, Nitromethane and 1,2,4-Trimethoxybenzene on the Fluorescence Emission Behavior of Select Monoaza- and Diazaarenes. Applied Spectroscopy.1992, 46, 1630-1635.
  2. In contrast to 1,3-Dimethoxybenzene, A13380, direct dilithiation with n-BuLi + TMEDA was feasible, giving, after reaction with TMS chloride, the 2,6-disilyl derivative as the major product in 55% yield: J. Org. Chem., 49, 4657 (1984).