Collagen I, bovine

Description

Collagen is a fibrous protein that consists of three α-chains that can combine to form a rope-like triple helix, providing tensile strength to the extracellular matrix (ECM) where it plays a key role in cell growth, differentiation, attachment, and cell migration. The α-chains contain GXY repeats. Glycine (G) is a small amino acid that fits well in the triple helix. X and Y are typically proline and hydroxyproline, which is critical for collagen stability. Type I is the most common fibrillar collagen (90%) and is mostly found in skin, bone, tendons, and other connective tissues.

Bovine tail collagen I can be prepared as a clear gel providing a 3D matrix or surface coated on tissue culture plates as a substrate for culturing primary cells such as keratinocytes and hepatocytes. The bovine tail collagen I offered here is supplied at a concentration of 5 mg/mL, providing the flexibility to dilute to lower concentrations.

Specifications

Concentration:	5 mg⁄ml, 5 mg/mL
Endotoxin Level:	≤10 EU/mL, ≤ 10 EU/ml
Form:	Liquid
Product Line:	Gibco®
Protein Form:	Native
Protein Subtype:	Collagen
Research Category:	Extracellular Matrix & Cell Adhesion
Shipping Condition:	Wet Ice
Species:	Cattle⁄Bovine
Validated Application:	Cell Culture

Contents & storage