4-Fluoro-2-nitroaniline, 98%

Name: 4-Fluoro-2-nitroaniline, 98%
SKU: A10685.36
Price: 345.00 EUR

CAS: 364-78-3 | C6H5FN2O2 | 156.12 g/mol

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Catalog number A10685.36

also known as A10685-36

Price (EUR)

345,00

Each

Quantity:

500 g

Request bulk or custom format

Price (EUR)

345,00

Each

Chemical Identifiers

CAS364-78-3

Specifications

Specification Sheet

Appearance (Color)Orange to brown to dark brown

FormCrystals or powder or crystalline powder

Identification (FTIR)Conforms

Water Content (Karl Fischer Titration)≤1%

Melting Point (clear melt)89.0-95.0°C

4-Fluoro-2-nitroaniline is used as a reagent in the preparation of 4-fluoro-o-phenylenediamine, 4-fluoro-N-ethyl-2-nitroaniline and N-(4-fluoro-2-nitrophenyl)-beta-alanine. It is also employed as a pharmaceutical intermediate. It acts as monodendate O-bonded ligand used in the coordination chemistry to form complexes with copper(II), nickel(II) and cobalt(II).

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
4-Fluoro-2-nitroaniline is used as a reagent in the preparation of 4-fluoro-o-phenylenediamine, 4-fluoro-N-ethyl-2-nitroaniline and N-(4-fluoro-2-nitrophenyl)-beta-alanine. It is also employed as a pharmaceutical intermediate. It acts as monodendate O-bonded ligand used in the coordination chemistry to form complexes with copper(II), nickel(II) and cobalt(II).

Solubility
Insoluble in water.

Notes
Incompatible with strong oxidizing agents, strong bases and strong acids.

RUO – Research Use Only

General References:

Nale, D. B.; Bhanage, B. M. Copper-catalyzed efficient synthesis of a 2-benzimidazolone scaffold from 2-nitroaniline and dimethyl carbonate via a hydrosilylation reaction. Green Chem. 2015, 17 (4), 2480-2486.
Baumann, M.; Baxendale, I. R.; Hornung, C. H.; Ley, S. V.; Rojo, M. V.; Roper, K. A. Synthesis of Riboflavines, Quinoxalinones and Benzodiazepines through Chemoselective Flow Based Hydrogenations. Molecules 2014, 19 (7), 9736-9759.