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2-Amino-4,6-dichloropyrimidine, 98%, Thermo Scientific Chemicals
Catalog number: A11330.22
100 g, Each
Thermo Scientific Chemicals
2-Amino-4,6-dichloropyrimidine, 98%, Thermo Scientific Chemicals
Catalog number: A11330.22
100 g, Each
Quantity
Catalog number: A11330.22
also known as A11330-22
Price (USD)
Price: 575.00
Online price: 496.65
Your price:
Quantity
-
Chemical Identifiers
CAS
56-05-3
IUPAC Name
4,6-dichloropyrimidin-2-amine
Molecular Formula
C4H3Cl2N3
InChI Key
JPZOAVGMSDSWSW-UHFFFAOYSA-N
SMILES
NC1=NC(Cl)=CC(Cl)=N1
Specifications
Specification SheetAppearance (Color)
Pale cream
Melting Point (clear melt)
218.0-225.0?C
Assay (GC)
≥97.5%
Form
Powder
Description
Microwave-assisted synthesis of pyrazolo [3, 4-d] pyrimidines from 2-amino-4, 6-dichloropyrimidine-5-carbaldehyde is under solvent-free conditions. A series of 6-alkynyl-2,4-diaminopyrimidine derivatives bearing various substituents at alkynyl moiety was prepared by the Sonogashira cross-coupling reaction of 2,4-diamino-6-iodopyrimidine using Pd(PPh3)2Cl2 as catalyst.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
Microwave-assisted synthesis of pyrazolo [3, 4-d] pyrimidines from 2-amino-4, 6-dichloropyrimidine-5-carbaldehyde is under solvent-free conditions. A series of 6-alkynyl-2,4-diaminopyrimidine derivatives bearing various substituents at alkynyl moiety was prepared by the Sonogashira cross-coupling reaction of 2,4-diamino-6-iodopyrimidine using Pd(PPh3)2Cl2 as catalyst.
Solubility
Insoluble in water, soluble in acetone, two monomer (VCM) and thermal toluene.
Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents.
Microwave-assisted synthesis of pyrazolo [3, 4-d] pyrimidines from 2-amino-4, 6-dichloropyrimidine-5-carbaldehyde is under solvent-free conditions. A series of 6-alkynyl-2,4-diaminopyrimidine derivatives bearing various substituents at alkynyl moiety was prepared by the Sonogashira cross-coupling reaction of 2,4-diamino-6-iodopyrimidine using Pd(PPh3)2Cl2 as catalyst.
Solubility
Insoluble in water, soluble in acetone, two monomer (VCM) and thermal toluene.
Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents.
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