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1-Bromo-3-chloropropane, 99%, Thermo Scientific Chemicals
Catalog number: A11395.30
250 g, Each
Thermo Scientific Chemicals
1-Bromo-3-chloropropane, 99%, Thermo Scientific Chemicals
Catalog number: A11395.30
250 g, Each
Quantity
Catalog number: A11395.30
also known as A11395-30
Price (EUR)
24,84 Online price
27,60
Each
Quantity
-
Chemical Identifiers
CAS
109-70-6
IUPAC Name
1-bromo-3-chloropropane
Molecular Formula
C3H6BrCl
InChI Key
MFESCIUQSIBMSM-UHFFFAOYSA-N
SMILES
ClCCCBr
Specifications
Specification SheetForm
Liquid
Comment
Material sourced in UK and US
Appearance (Color)
Clear colorless
Assay (GC)
≥98.5% (UK-sourced material)
Refractive Index
1.4845-1.4875 @ 20?C (UK-sourced material)
Description
1-Bromo-3-chloropropane is used in the preparation active pharmaceutical ingredient intermediate such as gemfibrozil and reproterol. It is also involved in the preparation of cardiovascular diseases and analgesic drugs materials. It is utilized as a phase separation reagent for the isolation of ribonucleic acid (RNA) in high quality. It is considered as a replacement of chloroform in nucleic acid separations.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
1-Bromo-3-chloropropane is used in the preparation active pharmaceutical ingredient intermediate such as gemfibrozil and reproterol. It is also involved in the preparation of cardiovascular diseases and analgesic drugs materials. It is utilized as a phase separation reagent for the isolation of ribonucleic acid (RNA) in high quality. It is considered as a replacement of chloroform in nucleic acid separations.
Solubility
Miscible with alcohols, chlorofom and ether. Immiscible with water.
Notes
Incompatible with strong oxidizing, reducing agents, amines, nitrides, azo/diazo compounds, alkali metals and epoxides.
1-Bromo-3-chloropropane is used in the preparation active pharmaceutical ingredient intermediate such as gemfibrozil and reproterol. It is also involved in the preparation of cardiovascular diseases and analgesic drugs materials. It is utilized as a phase separation reagent for the isolation of ribonucleic acid (RNA) in high quality. It is considered as a replacement of chloroform in nucleic acid separations.
Solubility
Miscible with alcohols, chlorofom and ether. Immiscible with water.
Notes
Incompatible with strong oxidizing, reducing agents, amines, nitrides, azo/diazo compounds, alkali metals and epoxides.
RUO – Research Use Only
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Safety and Handling
Classification of the substance or mixture
CLP classification - Regulation(EC) No 1272/2008
Acute oral toxicity
Category 4
Acute Inhalation Toxicity - Vapors
Category 3
Germ Cell Mutagenicity
Category 2
Specific target organ toxicity - (single exposure)
Category 3
Chronic aquatic toxicity
Category 3
Label Elements
Signal Word
Danger
Hazard Statements
H302 - Harmful if swallowed
H331 - Toxic if inhaled
H335 - May cause respiratory irritation
H341 - Suspected of causing genetic defects
H412 - Harmful to aquatic life with long lasting effects
EU Specific Hazard Statements
Combustible liquid
Precautionary Statements
P264 - Wash face, hands and any exposed skin thoroughly after handling
P280 - Wear protective gloves/protective clothing/eye protection/face protection
P301 + P330 + P331 - IF SWALLOWED: rinse mouth. Do NOT induce vomiting
P304 + P340 - IF INHALED: Remove person to fresh air and keep comfortable for breathing
P311 - Call a POISON CENTER or doctor/physician