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L-Leucine-4-nitroanilide, 99%, Thermo Scientific Chemicals
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Catalog number A11994.06
also known as A11994-06
Price (USD)/ Each
166.65
Special Offer
Online exclusive
Ends: 31-Dec-2024
196.00 Save 29.35 (15%)
-
Quantity:
5g
Price (USD)/ Each
166.65
Special Offer
Online exclusive
Ends: 31-Dec-2024
196.00 Save 29.35 (15%)
L-Leucine-4-nitroanilide, 99%, Thermo Scientific Chemicals
Catalog numberA11994.06
Price (USD)/ Each
166.65
Special Offer
Online exclusive
Ends: 31-Dec-2024
196.00 Save 29.35 (15%)
-
Chemical Identifiers
IUPAC Name(2S)-2-amino-4-methyl-N-(4-nitrophenyl)pentanamide
Molecular FormulaC12H17N3O3
InChI KeyAXZJHDNQDSVIDR-NSHDSACASA-N
SMILESCC(C)C[C@H](N)C(=O)NC1=CC=C(C=C1)[N+]([O-])=O
Molecular Weight (g/mol)251.29
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Specifications
Specification Sheet
Specification SheetFormCrystals or powder or crystalline powder
Assay (Non-aqueous acid-base Titration)≥98.5 to ≤101.5% (non-U.S. specification)
Melting Point (clear melt)87.0-93.0°C
CommentSpecification differs for U.S. and non-U.S. material where indicated
Appearance (Color)White to cream to pale yellow
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It is used to detect/evaluate functionality of amino peptidases. The compound is used in an ELISA assay to detect biological functionality of chicken amino peptidase produced by E. coli. It is also employed to characterize the native IRAP (placental leucine amino peptidase). Leu-pNA, Chromogenic Substrate is documented for use with pure samples as well as cell extracts in vitro.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
It is used to detect/evaluate functionality of amino peptidases. The compound is used in an ELISA assay to detect biological functionality of chicken amino peptidase produced by E. coli. It is also employed to characterize the native IRAP (placental leucine amino peptidase). Leu-pNA, Chromogenic Substrate is documented for use with pure samples as well as cell extracts in vitro.
Solubility
Soluble in DMSO (>100 mM), and methanol (>25 mM).
Notes
Store away from oxidizing agents. Keep the container tightly closed in a well ventilated place.
It is used to detect/evaluate functionality of amino peptidases. The compound is used in an ELISA assay to detect biological functionality of chicken amino peptidase produced by E. coli. It is also employed to characterize the native IRAP (placental leucine amino peptidase). Leu-pNA, Chromogenic Substrate is documented for use with pure samples as well as cell extracts in vitro.
Solubility
Soluble in DMSO (>100 mM), and methanol (>25 mM).
Notes
Store away from oxidizing agents. Keep the container tightly closed in a well ventilated place.
RUO – Research Use Only
A Bernkop-Schnürch.; M K Marschütz. Development and in vitro evaluation of systems to protect peptide drugs from aminopeptidase N.Pharm. Res.1997,14(2), 181-185.
E K Deniakina.; A D Nekliudov.; T A Loginova.; I A Krest’ianova.; Iu E Bartoshevich. Production and properties of an immobilized enzyme preparation with peptidase activity.Prikl Biokhim Mikrobiol.1985,21(2), 177-83.
E K Deniakina.; A D Nekliudov.; T A Loginova.; I A Krest’ianova.; Iu E Bartoshevich. Production and properties of an immobilized enzyme preparation with peptidase activity.Prikl Biokhim Mikrobiol.1985,21(2), 177-83.