Alexa Fluor 488™ phalloidin is a high-affinity filamentous actin (F-actin) probe conjugated to our bright, photostable, green-fluorescent Alexa Fluor™ 488 dye.
Also available as a room-temperature-stable, ready-to-use solution:
ActinGreen 488 Ready Probes Reagent.
See other Ready Probes ready-to-use imaging reagents and accessories ›•
Selectively stains F-actin•
Outstanding fluorescence performance•
Excitation/Emission: 495/518 nm•
Superior to antibody staining•
Optimal for fixed and permeabilized samplesGet Superior Results in Your Actin Staining StudiesPhalloidin is a bicyclic peptide belonging to a family of toxins isolated from the deadly
Amanita phalloides “death cap” mushroom and is commonly used in imaging applications to selectively label F-actin. Fluorescently-labeled phalloidin has several advantages over antibodies for actin labeling, including virtually identical binding properties with actin from different species of plants and animals, and low non-specific binding. Phalloidin binds F-actin with high selectivity, while Alexa Fluor™ 488 provides green fluorescence of unparalleled brightness and photostability.
Use in Multiple ApplicationsAlexa Fluor™ 488 phalloidin can be used to visualize and quantitate F-actin in tissue sections, cell cultures, or cell-free preparations. Alexa Fluor™ 488 phalloidin staining is fully compatible with other fluorescent stains used in cellular analyses, including fluorescent proteins, Qdot™ nanocrystals and other Alexa Fluor™ conjugates including secondary antibodies.
Read about labeling F-Actin with phallotoxins Find out more about our Alexa Fluor™ 488 productsCreate a Cellular Masterpiece with Alexa Fluor™ Phalloidin using the Cell Paint ToolSee the full line of Alexa Fluor™ Dye products