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      Alexa Fluor™ 488 Phalloidin

      Alexa Fluor™ 488 Phalloidin

      Catalog number:  A12379

       Related applications: Cell Structure

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      Description

      Alexa Fluor 488® phalloidin is a high-affinity filamentous actin (F-actin) probe conjugated to our bright, photostable, green-fluorescent Alexa Fluor® 488 dye.

      • Selectively stains F-actin
      • Outstanding fluorescence performance
      • Excitation/Emission: 495/518 nm
      • Superior to antibody staining
      • Optimal for fixed and permeabilized samples

      Get Superior Results in Your Actin Staining Studies
      Phalloidin is a bicyclic peptide belonging to a family of toxins isolated from the deadly Amanita phalloides “death cap" mushroom and is commonly used in imaging applications to selectively label F-actin. Fluorescently-labeled phalloidin has several advantages over antibodies for actin labeling, including virtually identical binding properties with actin from different species of plants and animals, and low non-specific binding. Phalloidin binds F-actin with high selectivity, while Alexa Fluor® 488 provides green fluorescence of unparalleled brightness and photostability.

      Use in Multiple Applications
      Alexa Fluor® 488 phalloidin can be used to visualize and quantitate F-actin in tissue sections, cell cultures, or cell-free preparations. Alexa Fluor® 488 phalloidin staining is fully compatible with other fluorescent stains used in cellular analyses, including fluorescent proteins, Qdot® nanocrystals and other Alexa Fluor® conjugates including secondary antibodies.

      Read about labeling F-Actin with phallotoxins

      Find out more about our Alexa Fluor® 488 products

      Create a Cellular Masterpiece with Alexa Fluor® Phalloidin using the Cell Paint Tool

      See the full line of Alexa Fluor® Dye products
      For Research Use Only. Not for use in diagnostic procedures.

      Figures

      Specifications

      Label or Dye: Alexa Fluor™ 488
      Sub-Cellular Localization: Actin, Cytoskeleton
      Excitation⁄Emission (nm): 495⁄518
      Product Line: Alexa Fluor™
      Product Size: 300 units
      Shipping Condition: Room Temperature

      Contents & storage

      Store in freezer (-5 to -30°C) and protect from light.

      Documents

      Manuals & protocols