Alexa Fluor™ 488 Phalloidin

Catalog number:  A12379

Related applications:

Cell Structure

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Alexa Fluor 488® phalloidin is a high-affinity filamentous actin (F-actin) probe conjugated to our bright, photostable, green-fluorescent Alexa Fluor® 488 dye.

Also available as a room-temperature-stable, ready-to-use solution: ActinGreen 488 Ready Probes Reagent.
See other Ready Probes ready-to-use imaging reagents and accessories ›

Selectively stains F-actin
Outstanding fluorescence performance
Excitation/Emission: 495/518 nm
Superior to antibody staining
Optimal for fixed and permeabilized samples

Get Superior Results in Your Actin Staining Studies
Phalloidin is a bicyclic peptide belonging to a family of toxins isolated from the deadly Amanita phalloides “death cap" mushroom and is commonly used in imaging applications to selectively label F-actin. Fluorescently-labeled phalloidin has several advantages over antibodies for actin labeling, including virtually identical binding properties with actin from different species of plants and animals, and low non-specific binding. Phalloidin binds F-actin with high selectivity, while Alexa Fluor® 488 provides green fluorescence of unparalleled brightness and photostability.

Use in Multiple Applications
Alexa Fluor® 488 phalloidin can be used to visualize and quantitate F-actin in tissue sections, cell cultures, or cell-free preparations. Alexa Fluor® 488 phalloidin staining is fully compatible with other fluorescent stains used in cellular analyses, including fluorescent proteins, Qdot® nanocrystals and other Alexa Fluor® conjugates including secondary antibodies.

Read about labeling F-Actin with phallotoxins

Find out more about our Alexa Fluor® 488 products

Create a Cellular Masterpiece with Alexa Fluor® Phalloidin using the Cell Paint Tool

See the full line of Alexa Fluor® Dye products
For Research Use Only. Not for use in diagnostic procedures.


Excitation/Emission: 495⁄518
Label or Dye: Alexa Fluor™ 488
Product Line: Alexa Fluor™
Shipping Condition: Room Temperature
Sub Cellular Localization: Actin, Cytoskeleton
Label Type: Alexa Fluor Dyes

Contents & storage

Store in freezer (-5 to -30°C) and protect from light.