Thermo Scientific Chemicals

tert-Butyl carbazate, 98+%, Thermo Scientific Chemicals

Catalog number: A12383.36
500 g, Each
Thermo Scientific Chemicals

tert-Butyl carbazate, 98+%, Thermo Scientific Chemicals

Catalog number: A12383.36
500 g, Each
Quantity
Catalog number: A12383.36
also known as A12383-36
Price (USD)
Quantity
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Chemical Identifiers

CAS
870-46-2
IUPAC Name
(tert-butoxy)carbohydrazide
Molecular Formula
C5H12N2O2
InChI Key
DKACXUFSLUYRFU-UHFFFAOYSA-N
SMILES
CC(C)(C)OC(=O)NN
Appearance (Color)
White
Assay (GC)
>98.0%
Solution Test
5% w/v in ethanol: clear solution
Form
crystals or fused solid

Description

tert-Butyl carbazate is used in a palladium-catalyzed cross-coupling with vinyl halides to prepare N-Boc-N-alkenylhydrazines. It is utilized in solid phase peptide synthesis and in the optical purity determination of alfa-amino aldehyde. It reacts with aldehydes to get hydrazones, which finds application as an intermediate in the synthesis of HIV-1 protease inhibitors. In addition to this, it is used as a starting material for the preparation of BOC-azide, sulfonic and carboxylic hydrazides.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
tert-Butyl carbazate is used in a palladium-catalyzed cross-coupling with vinyl halides to prepare N-Boc-N-alkenylhydrazines. It is utilized in solid phase peptide synthesis and in the optical purity determination of alfa-amino aldehyde. It reacts with aldehydes to get hydrazones, which finds application as an intermediate in the synthesis of HIV-1 protease inhibitors. In addition to this, it is used as a starting material for the preparation of BOC-azide, sulfonic and carboxylic hydrazides.

Solubility
Soluble in ethanol and methanol.

Notes
Store in a cool place. Incompatible with strong oxidizing agents and strong bases.
RUO – Research Use Only

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