Thermo Scientific Chemicals

3-Hydroxy-4-methoxybenzaldehyde, 98%, Thermo Scientific Chemicals

Catalog number: A12866.22
100 g, Each
Thermo Scientific Chemicals

3-Hydroxy-4-methoxybenzaldehyde, 98%, Thermo Scientific Chemicals

Catalog number: A12866.22
100 g, Each
Quantity
Catalog number: A12866.22
also known as A12866-22
Price (USD)
Price: 182.00
Online price: 154.65
Your price:
Quantity
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Chemical Identifiers

CAS
621-59-0
IUPAC Name
3-hydroxy-4-methoxybenzaldehyde
Molecular Formula
C8H8O3
InChI Key
JVTZFYYHCGSXJV-UHFFFAOYSA-N
SMILES
COC1=CC=C(C=O)C=C1O
Form
Crystals or powder or crystalline powder
Melting Point (clear melt)
111.0-117.0°C
Assay (GC)
≥97.5%
Appearance (Color)
White to cream to gray to pale brown

Description

3-Hydroxy-4-methoxybenzaldehyde acts as a precursor for the stereoselective synthesis of the anticancer drug (Z)-combretastatin A-4 and glycitein. It also used as an important raw material for the preparation of morphine. Further, it is involved in the preparation of Schiff- bases by reacting with furan-2-carboxylic acid hydrazide and thiophene-2-carboxylic acid hydrazide. In addition to this, it is used to prepare (Z)-2-(3-hydroxy-4-methoxybenzylidene)-1-azabicyclo[2.2.2]octan-3-one by reacting with with1-azabicyclo[2.2.2]octan-3-one.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
3-Hydroxy-4-methoxybenzaldehyde acts as a precursor for the stereoselective synthesis of the anticancer drug (Z)-combretastatin A-4 and glycitein. It also used as an important raw material for the preparation of morphine. Further, it is involved in the preparation of Schiff- bases by reacting with furan-2-carboxylic acid hydrazide and thiophene-2-carboxylic acid hydrazide. In addition to this, it is used to prepare (Z)-2-(3-hydroxy-4-methoxybenzylidene)-1-azabicyclo[2.2.2]octan-3-one by reacting with with1-azabicyclo[2.2.2]octan-3-one.

Solubility
Soluble in acetone and methanol.

Notes
Air sensitive. Store in a cool place. Incompatible with strong oxidizing agents and strong bases.
RUO – Research Use Only

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