DL-Proline is used as an agonist of glycine receptors. It acts as a catalyst for aldol condensation. It is an essential component of collagen. It plays a significant role in the immune system and strengthening of heart muscles. It is an osmoprotectant and therefore is used in many pharmaceutical, biotechnological applications.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
DL-Proline is used as an agonist of glycine receptors. It acts as a catalyst for aldol condensation. It is an essential component of collagen. It plays a significant role in the immune system and strengthening of heart muscles. It is an osmoprotectant and therefore is used in many pharmaceutical, biotechnological applications.
Solubility
Soluble in water and absolute alcohol. Insoluble in ether, butanol and isopropanol.
Notes
Incompatible with strong oxidizing agents.
RUO – Research Use Only
General References:
- Serb, M.; Englert, U. Unexpected proline coordination in the copper chain polymer [Cu([mu]-Cl)2([mu]-dl-proline-[kappa]2O:O')]1[infinity]. Acta Crystallogr. Sect. C-Cryst. Struct. Commun. 2015, 71 (4), 271-275.
- Tan, H.; Liu, H.; Chen, X.; Chen, H.; Qiu, S. Racemic total synthesis of dactyloidin and demethyldactyloidin through the dl-proline-catalyzed Knoevenagel condensation/[4+ 2] cycloaddition cascade. Org. Biomol. Chem. 2015, 13 (39), 9977-9983.