Thermo Scientific Chemicals

N-Boc-L-proline, 99%, Thermo Scientific Chemicals

Catalog number: A13744.14
25 g, Each
Thermo Scientific Chemicals

N-Boc-L-proline, 99%, Thermo Scientific Chemicals

Catalog number: A13744.14
25 g, Each
Quantity
Catalog number: A13744.14
also known as A13744-14
Price (USD)

Chemical Identifiers

CAS
15761-39-4
IUPAC Name
1-[(tert-butoxy)carbonyl]pyrrolidine-2-carboxylic acid
Molecular Formula
C10H17NO4
InChI Key
ZQEBQGAAWMOMAI-UHFFFAOYNA-N
SMILES
CC(C)(C)OC(=O)N1CCCC1C(O)=O
Form
Crystals or powder or crystalline powder
Melting Point (clear melt)
131.0-137.0°C
Assay (Aqueous acid-base Titration)
≥98.5 to ≤101.5%
Optical Rotation
-58° to -62° (C=1 in acetic acid)
Appearance (Color)
White

Description

N-Boc-L-proline is used as an intermediate in organic synthesis. It is also used to prepare daclatasvir, which inhibits the hepatitis C virus (HCV) non-structural 5A (NS5A) protein. Further, it is used as a drug in the treatment of hepatitis C virus (HCV).

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
N-Boc-L-proline is used as an intermediate in organic synthesis. It is also used to prepare daclatasvir, which inhibits the hepatitis C virus (HCV) non-structural 5A (NS5A) protein. Further, it is used as a drug in the treatment of hepatitis C virus (HCV).

Solubility
Soluble in acetic acid.

Notes
Moisture and light sensitive. Incompatible with strong oxidizing agents.
RUO – Research Use Only

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