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Thermo Scientific Chemicals
2-Amino-4-methylpyridine, 98%
CAS: 695-34-1 | C6H8N2 | 108.144 g/mol
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化學識別
CAS695-34-1
IUPAC Name4-methylpyridin-2-amine
Molecular FormulaC6H8N2
InChI KeyORLGLBZRQYOWNA-UHFFFAOYSA-N
SMILESCC1=CC=NC(N)=C1
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規格
規格表
規格表FormCrystals or powder or crystalline powder or crystalline flakes
Assay (Non-aqueous acid-base Titration)≥97.5 to ≤102.5%
Water Content (Karl Fischer Titration)<1.0%
Appearance (Color)White to pale yellow or pale cream to cream or pale pink or pale brown
Identification (FTIR)Conforms
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2-Amino-4-methylpyridine has been used in the synthesis of 2-amino-4-methylpyridinium 2-hydroxybenzoate. It is potent inhibitor of NOS2 (iNOS) in vitro. It is used as pharmaceutical intermediate.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
2-Amino-4-methylpyridine has been used in the synthesis of 2-amino-4-methylpyridinium 2-hydroxybenzoate. It is potent inhibitor of NOS2 (iNOS) in vitro. It is used as pharmaceutical intermediate.
Solubility
Soluble in water (41 mg/ml at 20°C), lower alcohols (slightly), chloroform, ethyl acetate, and DMF.
Notes
Hygroscopic. Incompatible with oxidizing agents and moisture. Store under dry inert gas. Protect from humidity and water. Store at -20°C.
2-Amino-4-methylpyridine has been used in the synthesis of 2-amino-4-methylpyridinium 2-hydroxybenzoate. It is potent inhibitor of NOS2 (iNOS) in vitro. It is used as pharmaceutical intermediate.
Solubility
Soluble in water (41 mg/ml at 20°C), lower alcohols (slightly), chloroform, ethyl acetate, and DMF.
Notes
Hygroscopic. Incompatible with oxidizing agents and moisture. Store under dry inert gas. Protect from humidity and water. Store at -20°C.
RUO – Research Use Only
General References:
- Madhukar Hemamalini; Hoong-Kun Fun. 2-Amino-4-methyl-pyridinium 2-hy-droxy-benzoate. Acta Crystallographica Section E.2010, 66 (Pt 8), o2151-o2152.
- W S Faraci; A A Nagel; K A Verdries; L A Vincent; H Xu; L E Nichols; J M Labasi; E D Salter; E R Pettipher. 2-Amino-4-methylpyridine as a potent inhibitor of inducible NO synthase activity in vitro and in vivo. British Journal of Pharmacology.1996, 119 (6), 1101-1108.