2-Amino-5-chlorobenzoic acid, 98%
2-Amino-5-chlorobenzoic acid, 98%
2-Amino-5-chlorobenzoic acid, 98%
2-Amino-5-chlorobenzoic acid, 98%
Thermo Scientific Chemicals

2-Amino-5-chlorobenzoic acid, 98%

CAS: 635-21-2 | C7H6ClNO2 | 171.58 g/mol
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5 g
25 g
100 g
Catalog number A14329.14
also known as A14329-14
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Chemical Identifiers
CAS635-21-2
IUPAC Name2-amino-5-chlorobenzoic acid
Molecular FormulaC7H6ClNO2
InChI KeyIFXKXCLVKQVVDI-UHFFFAOYSA-N
SMILESNC1=CC=C(Cl)C=C1C(O)=O
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SpecificationsSpecification SheetSpecification Sheet
Appearance (Color)Pale cream to cream to pale brown
Assay (Aqueous acid-base Titration)≥97.5 to ≤102.5%
Water Content (Karl Fischer Titration)≤1%
Assay (HPLC)≥97.5%
FormCrystals or powder or crystalline powder or lumps
2-Amino-5-chlorobenzoic acid is used in the preparation of disease-modifying antirheumatic drugs (DMARDs). Also used to produce 6-chloro-3H-quinazolin-4-one at temperature of 180°C.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
2-Amino-5-chlorobenzoic acid is used in the preparation of disease-modifying antirheumatic drugs (DMARDs). Also used to produce 6-chloro-3H-quinazolin-4-one at temperature of 180°C.

Solubility
Soluble in water.

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Incompatible with oxidizing agents.
RUO – Research Use Only

General References:

  1. Stephen P. Coburn.; J. Dennis Mahuren. A versatile cation-exchange procedure for measuring the seven major forms of vitamin B6 in biological samples 1. Analytical Biochemistry. 1983, 129 (2), 310-317.
  2. R. I. Fryer.; P. Zhang.; R. Rios. The Synthesis of Substituted 2-Aminophenyl Heterocyclic Ketones. Synthetic Communications: An International Journal for Rapid Communication of Synthetic Organic Chemistry. 1993, 23 (7), 985-992.