2-Chloropyridine, 99%

Name: 2-Chloropyridine, 99%
SKU: A14866.22

CAS: 109-09-1 | C5H4ClN | 113.544 g/mol

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Catalog number A14866.22

also known as A14866-22

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100 g

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Chemical Identifiers

CAS109-09-1

IUPAC Name2-chloropyridine

Molecular FormulaC5H4ClN

InChI KeyOKDGRDCXVWSXDC-UHFFFAOYSA-N

SMILESClC1=CC=CC=N1

Specifications

Specification Sheet

FormLiquid

Refractive Index1.5315-1.5345 @ 20?C

Appearance (Color)Clear colorless to pale yellow

Assay (GC)≥98.5%

2- Chloropyridine is used as an intermediate chemical in the production of various pyrithione, for use in cosmetics, personal care products and pharmaceutical products.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
2- Chloropyridine is used as an intermediate chemical in the production of various pyrithione, for use in cosmetics, personal care products and pharmaceutical products.

Solubility
Soluble in water (27g/L).

Notes
Keep container tightly closed. Store away from oxidizing agents.

RUO – Research Use Only

General References:

Sabine Choppin.; Philippe Gros.; Yves For. Unusual C-6 Lithiation of 2-Chloropyridine-Mediated by BuLi-Me2N(CH2)2OLi. New Access to 6-Functional-2-chloropyridines and Chloro-bis-heterocycles. Org. Lett. 2002, 2, (6), 803-805.
Meriç Bakiler.; I.V. Maslov.; Sevim Akyüzc.Theoretical study of the vibrational spectra of 2-chloropyridine metal complexes. I. Calculation and analysis of the IR spectrum of 2-chloropyridine. Journal of Molecular Structure. 1999, 475, (1), 83-92.
Reaction with the unimetal suberbase complex formed from 2 mol of n-BuLi and I mol of 2-(Dimethyl amino) ethanol, B23616, in hexane, gives products resulting from apparent metallation at the 6-position, providing useful access to 6-functionalized 2-chloropyridines: Org. Lett., 2, 803 (2000). See also 2-Methoxypyridine, A13675, for a similar effect.