Thermo Scientific™
LanthaScreen™ TR-FRET Glucocorticoid Receptor Competitive Binding Kit
Description
The LanthaScreen® TR-FRET Glucocorticoid Receptor Competitive Binding Assay Kit provides a sensitive and robust method for high-throughput screening (HTS) of ligands for glucocorticoid receptor (GR). The kit uses a human GR ligand-binding domain (GR-LBD) tagged with glutathione S-transferase (GST) (also available separately), a terbium-labeled anti-GST antibody, and a fluorescent small-molecule GR ligand (Fluormone™ GS1) in a homogeneous mix-and-read assay format.The Lanthascreen Gluococorticoid Receptor Competitive Binding Assay is:
• Complete & ready-to-use out of the box—all reagents included, just add your test compounds
• High throughput compatible—TR-FRET assays in a 384-well plate
• Convenient—components available in bulk sizes for larger screening needs
WARNING: Reproductive Harm - www.P65Warnings.ca.gov
For Research Use Only. Not for use in diagnostic procedures.
Specifications
| Product Line: | LanthaScreen® |
|---|---|
| Validated Application: | Competitive Binding Assay, Nuclear Receptor Assay |
Contents & storage
1 tube GR Ligand Binding Domain Recombinant Protein (store at -68 to -85°C)
1 tube of Fluormone GS1 (store at -5 to -30°C)
2 bottles Buffer (store at -5 to -30°C)
1 tube Tb-Anti-GST Ab (store at -5 to -30°C)
5 tubes GR Stabilizing Peptide (store at -5 to -30°C)
1 tube of DTT (store at -5 to -30°C)
1 tube of Fluormone GS1 (store at -5 to -30°C)
2 bottles Buffer (store at -5 to -30°C)
1 tube Tb-Anti-GST Ab (store at -5 to -30°C)
5 tubes GR Stabilizing Peptide (store at -5 to -30°C)
1 tube of DTT (store at -5 to -30°C)
