1,3-Dichloro-2-propanol biotransformation to epichlorohydrin by the whole cells of recombinant Escherichia coli via resin-based in situ product removal has been investigated. It is used in the synthesis of glycerol, in the production of plastics and textiles and in the synthesis of pharmaceuticals. Also used as a solvent and as a cement for celluloid. It is also present in some foods, e.g. soy sauce, soup spices and instant soups, from hydrolization of proteins.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
1,3-Dichloro-2-propanol biotransformation to epichlorohydrin by the whole cells of recombinant Escherichia coli via resin-based in situ product removal has been investigated. It is used in the synthesis of glycerol, in the production of plastics and textiles and in the synthesis of pharmaceuticals. Also used as a solvent and as a cement for celluloid. It is also present in some foods, e.g. soy sauce, soup spices and instant soups, from hydrolization of proteins.
Solubility
Fully miscible in water.
Notes
Stable under recommended storage conditions. Incompatible with oxidizing agents.
RUO – Research Use Only
Shu-Ping Zou; Er-Hong Du; Zhong-Ce Hu; Yu-Guo Zheng. Enhanced biotransformation of 1,3-dichloro-2-propanol to epichlorohydrin via resin-based in situ product removal process. Biotechnology Letters. 2013, 35, (6),937-942
T.Nakamura; T.Nagasawa; F.Yu; I.Watanabe; H.Yamada. Resolution and some properties of enzymes involved in enantioselective transformation of 1,3-dichloro-2-propanol to (R)-3-chloro-1,2-propanediol by Corynebacterium sp. strain N-1074. Journal of Bacteriology. 1992, 174, (23),7613-7619