Thermo Scientific™

2'-Deoxyuridine, 99%

25g, Each
Thermo Scientific™

2'-Deoxyuridine, 99%

25g, Each
Quantity
Catalog number: A16026.14
also known as A16026-14
Price (USD)
126.00 / Each
Your Price:
Quantity
-

Chemical Identifiers

CAS
951-78-0
IUPAC Name
1-[4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,3,4-tetrahydropyrimidine-2,4-dione
Molecular Formula
C9H12N2O5
InChI Key
MXHRCPNRJAMMIM-UHFFFAOYNA-N
SMILES
OCC1OC(CC1O)N1C=CC(=O)NC1=O
Melting Point (clear melt)
157-168?C
Appearance (Color)
White
Assay (HPLC)
≥98.5%
Form
Powder
Optical Rotation
+52.0? ? 2.0? (c=1, 1M NaOH)

Description

This Thermo Scientific brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific.
Applications
2′-Deoxyuridine is frequently halogenated to create thymidine analogues useful for studies of DNA synthesis and degradation mechanisms. Derivatized 2′-Deoxyuridines used as labeling substrates include chloro-2′-deoxyuridine (CldU), bromodeoxyuridine (BrdU) and/or iododeoxyuridine (IdU). Other useful analogues of 2′-deoxyuridine include 5-ethynyl-2′-deoxyuridine (DdU) and 5-hydroxymethyl-2′-deoxyuridine (HmdU). Laboratory suppression of deoxyuridine is used to diagnose megaloblastic anemias due to vitamin B12 and folate deficiencies. Deoxyuridine (dU) is used to indirectly determine if there are sufficient levels of folate and cobalamin in cell or tissue samples.

Solubility
Soluble in water.

Notes
Keep container tightly sealed. Store in cool, dry conditions in well sealed containers. Incompatible with oxidizing agents. It is sensitive to air.
RUO – Research Use Only

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