Heparin sodium salt, from porcine intestinal mucosa, IU≥100/mg, Thermo Scientific Chemicals
Element SearchElement SearchStructure SearchStructure Search
Heparin sodium salt, from porcine intestinal mucosa, IU≥100/mg, Thermo Scientific Chemicals
Thermo Scientific Chemicals

Heparin sodium salt, from porcine intestinal mucosa, IU≥100/mg, Thermo Scientific Chemicals

Heparin Sodium Salt, CAS # 9041-08-1, is derived from porcine intestinal mucosa and shows blood anti-coagulant activity.
Have Questions?
Change viewbuttonViewtableView
Quantity:
250 mg
1 g
5 g
ChemDexTry the chem dexTM web app
This chemical may require us to obtain additional information for our regulatory and chemical compliance records. If required, we will contact you for this information once your order is placed.
Catalog number A16198.MD
also known as A16198-MD
Price (USD)/ Each
-
Quantity:
250 mg
Request bulk or custom format
Chemical Identifiers
MDL NumberMFCD00081689
CAS9041-08-1
SpecificationsSpecification SheetSpecification Sheet
CommentMaterial Sourced in UK and US
Elemental AnalysisN: 1.3 - 2.5% (dry wt.)
Loss on Drying≤ 8.0%
Optical Rotation≥ 45? (c=1.5, water) (UK Sourced Material)
FormPowder
View more
Heparin sodium salt is used as a blood anti-coagulant. It is also used as an effective inhibitor of mesenchymal cell proliferation. Further, it binds to antithrombin III, which inhibits coagulation proteases. It is used as a major component of serum free media for preventing cell aggregation. It is also used as an anti-cancer agent in in vitro cancer research.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

  • Heparin sodium salt displays anti-coagulant activity. It can also efficiently inhibit mesenchymal cell proliferation and promotes the proliferation of primary epithelial cells
  • This compound can bind to antithrombin III and inhibit coagulation proteases

Applications

  • In in vitro studies, it is used as the main component of serum-free media to prevent cell aggregation
  • Heparin sodium salt can also induce the growth of human embryonic stem cells in a defined serum-free medium, acting as a cofactor for a basic fibroblast growth factor (FGF-2)
  • It is also applied in laboratory studies related to stem cell differentiation and growth
  • In in vitro studies, this compound exhibits cytotoxic action inducing cancer cell death by interfering with transcription factor activity
RUO – Research Use Only

General References:

  1. d’Angelo, I.; Oliviero, O.; Ungaro, F.; Quaglia, F.; Netti, P. A. Engineering strategies to control vascular endothelial growth factor stability and levels in a collagen matrix for angiogenesis: The role of heparin sodium salt and the PLGA-based microsphere approach. Acta Biomater. 2013, 9 (7), 7389-7398.
  2. Bhalerao, U. M.; Valiveti, A. K.; Acharya, J.; Halve, A. K.; Kaushik, M. P. Controlled release studies of antimalarial 1, 3, 5-trisubstituted-2-pyrazolines from biocompatible chitosan-heparin Layer-by-Layer (LbL) self assembled thin films. Colloids Surf., B 2015, 125, 151-159.