1-Naphthyl isocyanate, 98%

Name: 1-Naphthyl isocyanate, 98%
SKU: A17200.06
Price: 52.40 EUR

CAS: 86-84-0 | C11H7NO | 169.183 g/mol

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Catalog number A17200.06

also known as A17200-06

Price (EUR)

52,40

Each

Quantity:

5 g

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Price (EUR)

52,40

Each

Chemical Identifiers

CAS86-84-0

IUPAC Name1-isocyanatonaphthalene

Molecular FormulaC11H7NO

InChI KeyBDQNKCYCTYYMAA-UHFFFAOYSA-N

SMILESO=C=NC1=C2C=CC=CC2=CC=C1

Specifications

Specification Sheet

Appearance (Color)Clear colorless to yellow

FormLiquid

Assay (GC)≥97.5%

Identification (FTIR)Conforms

Refractive Index1.6310-1.6350 @ 20°C

1-Naphthyl isocyanate is used in the preparation of cationic aromatic urethane. It is useful for the study of cholangiolitic hepatotoxicity in laboratory animals. It is also employed as separate enantiomers of beta-blockers.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
1-Naphthyl isocyanate is used in the preparation of cationic aromatic urethane. It is useful for the study of cholangiolitic hepatotoxicity in laboratory animals. It is also employed as separate enantiomers of beta-blockers.

Solubility
Miscible with alcohol, chloroform and diethyl ether.

Notes
Moisture and light sensitive. Incompatible with strong oxidizing agents and alcohols.

RUO – Research Use Only

General References:

Belal, F.; Walash, M.; El-Enany, N.; Zayed, S. Highly sensitive HPLC method for assay of aliskiren in human plasma through derivatization with 1-naphthyl isocyanate using UV detection. J. Chromatogr. B 2013, 933, 24-29.
McEntyre, C. J.; Slow, S.; Lever, M. Measurement of plasma free choline by high performance liquid chromatography with fluorescence detection following derivatization with 1-naphthyl isocyanate. Anal. Chim. Acta 2009, 644 (1-2), 90-94.