IL-1 beta Antibody (CRM56), FITC conjugate, Molecular Probes™

Catalog number: A18465

Invitrogen™  Related applications: Flow Cytometry

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Description

The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2.
For Research Use Only. Not for use in diagnostic procedures.

Specifications

Reactivity: Human
Validated Application: Flow Cytometry
Host Species: Mouse
SubClass (Isotype): IgG1
Clonality: Monoclonal
Clone ID: CRM56
Antibody Fragment: Whole Antibody
Target Gene: interleukin 1, beta
Gene ID: 3553
Gene Symbol: IL1B
Gene Aliases: IL-1, IL1-BETA, IL1F2
Label or Dye: Fluorescein (FITC)
Excitation⁄Emission (nm): 488⁄519
Excitation Class: Visible
Concentration: 0.025 mg⁄ml
Form: Liquid
Number of Reactions: 25 Tests
For Use With (Equipment): Attune® Acoustic Focusing Cytometer
Product Size: 25 tests
Other Additives: Sodium Azide Preservative

Contents & storage

Store in refrigerator (2–8°C).

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Manuals & protocols

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