NK1.1 / Ly-55 Antibody (PK136), PE conjugate, Molecular Probes™

Catalog number: A18483

Invitrogen™  Related applications: Flow Cytometry

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Description

Killer cell lectin-like receptor subfamily B, member 1, also known as KLRB1, NKR-P1A or CD161 (cluster of differentiation 161), is a human gene. Natural killer (NK) cells are lymphocytes that mediate cytotoxicity and secrete cytokines after immune stimulation. Several genes of the C-type lectin superfamily, including the rodent NKRP1 family of glycoproteins, are expressed by NK cells and may be involved in the regulation of NK cell function. The KLRB1 protein contains an extracellular domain with several motifs characteristic of C-type lectins, a transmembrane domain, and a cytoplasmic domain. The KLRB1 protein, NKR-P1A or CD161, is classified as a type II membrane protein because it has an external C terminus. NKR-P1A, the receptor encoded by the KLRB1 gene, recognizes Lectin Like Transcript-1 (LLT1) as a functional ligand.
For Research Use Only. Not for use in diagnostic procedures.

Specifications

Reactivity: Mouse
Validated Application: Flow Cytometry
Host Species: Mouse
SubClass (Isotype): IgG2a, kappa
Clonality: Monoclonal
Clone ID: PK136
Antibody Fragment: Whole Antibody
Target Gene: killer cell lectin-like receptor subfamily B member 1C
Gene ID: 17059
Gene Symbol: Klrb1c
Gene Aliases: CD161, Ly55c, Ly59, NK1.1, NKR-P1.9, NKRP1, NKRP140, Nk1, Nk1.2, Nkrp1c
Label or Dye: R-PE
Excitation⁄Emission (nm): 496⁄578
Excitation Class: Visible
Concentration: 0.2 mg⁄ml
Form: Liquid
Number of Reactions: 200 Tests
For Use With (Equipment): Attune® Acoustic Focusing Cytometer
Product Size: 50 µg
Other Additives: Sodium Azide Preservative

Contents & storage

Store in refrigerator (2–8°C).

Documents

Manuals & protocols

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