IL-4 Antibody (11B11), APC conjugate, Molecular Probes™

Catalog number: A18500

Invitrogen™  Related applications: Flow Cytometry

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Description

The protein encoded by this gene is a pleiotropic cytokine produced by activated T cells. This cytokine is a ligand for interleukin 4 receptor. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play a central role in mediating the immune regulatory signal of this cytokine. This gene, IL3, IL5, IL13, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL13. This gene, IL13 and IL5 are found to be regulated coordinately by several long-range regulatory elements in an over 120 kilobase range on the chromosome. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
For Research Use Only. Not for use in diagnostic procedures.

Specifications

Reactivity: Mouse
Validated Application: Flow Cytometry
Host Species: Rat
SubClass (Isotype): IgG1, kappa
Clonality: Monoclonal
Clone ID: 11B11
Antibody Fragment: Whole Antibody
Target Gene: interleukin 4
Gene ID: 16189
Gene Symbol: Il4
Gene Aliases: RP23-188H3.4, BSF-1, Il-4
Label or Dye: APC (Allophycocyanin)
Excitation⁄Emission (nm): 650⁄660
Excitation Class: Visible
Concentration: 0.2 mg⁄ml
Form: Liquid
Number of Reactions: 200 Tests
For Use With (Equipment): Attune® Acoustic Focusing Cytometer
Product Size: 50 µg
Other Additives: Sodium Azide Preservative

Contents & storage

Store in refrigerator (2–8°C).

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Manuals & protocols

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