N,N'-Diisopropilcarbodiimida, 99 %, Thermo Scientific Chemicals

N,N'-diisopropilcarbodiimida Alfa Aesar, 99 %, cantidad:50g, punto de ebullición:De 145 a 148 °C, peso molecular:126,203; Porcentaje de pureza:99 %, Beilstein:878281, CAS:693-13-0, ChEBI:CHEBI:53092, Densidad:0,81, Información DOT:Clase de peligro:6,1; grupo de embalaje:I, número EINECS:211-743-7

Número de catálogo	Cantidad
A19292.14	25 g

Número de catálogo A19292.14

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Identificadores químicos

CAS693-13-0

IUPAC Name(propan-2-yl)({[(propan-2-yl)imino]methylidene})amine

Molecular FormulaC7H14N2

InChI KeyBDNKZNFMNDZQMI-UHFFFAOYSA-N

SMILESCC(C)N=C=NC(C)C

Especificaciones Specification Sheet

FormLiquid

CommentMaterial Sourced in UK and US

Refractive Index1.4320-1.4350 @ 20?C (UK Sourced Material)

Appearance (Color)Clear colorless to yellow

CommentMay form a small amount of crystalline solid on standing that re-dissolves on warming

N,N'-Diisopropylcarbodiimide is used as a reagent in synthetic organic chemistry. It serves as a chemical intermediate and as a stabilizer for Sarin (chemical weapon). It is also used in the synthesis of peptide and nucleic acid. Further, it is used as an antineoplastic and involved in the treatment of malignant melanoma and sarcomas. In addition to this, it is used in the synthesis of acid anhydride, aldehyde, ketone and isocyanate.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Aplicaciones
La N,N′-diisopropilcarbodiimida se utiliza como reactivo en la química orgánica sintética. Sirve como intermediario químico y como estabilizador para el sarín (arma química). Se usa en la síntesis del ácido nucleico y péptido. Además, se utiliza como antineoplásico y participa en el tratamiento del melanoma maligno y los sarcomas. También se utiliza en la síntesis del anhídrido ácido, aldehído, cetona e isocianato.

Solubilidad
Soluble en cloroformo, cloruro de metileno, acetonitrilo, dioxano, dimetilformamida y tetrahidrofurano.

Notas
Sensible a la humedad. Almacenar en un lugar fresco. Incompatible con agentes oxidantes y ácidos.

RUO – Research Use Only

General References:

Reagent for peptide coupling: J. Org. Chem., 44, 5000 (1979). Has the advantage over N,N'-Dicyclohexyl carbodiimide, A10973 in solid phase peptide syntheses that the urea by-product is more soluble in organic solvents and hence more readily separated from the polymer support. For peptide reagents, see Appendix 6.
Ogawa, T.; Usuki, N.; Nakazono, K.; Koyama, Y.; Takata, T. Linear-cyclic polymer structural transformation and its reversible control using a rational rotaxane strategy. Chem. Commun. 2015, 51 (26), 5606-5609.
Smith, J. M.; Moreno, J.; Boal, B. W.; Garg, N. K. Cascade Reactions: A Driving Force in Akuammiline Alkaloid Total Synthesis. Angew. Chem. Int. Ed. 2015, 54 (2), 400-412.