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Invitrogen
Human NEK6, GST Tag Recombinant Protein
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Product Details
A31519
Product Specifications
Species
Human
Expression System
Insect cells
Amino acid sequence
Full length
Tag
GST-tag
Molecular weight
62.4 kDa
Class
Recombinant
Type
Protein
Conjugate
Form
Liquid
Concentration
See Label
Amount
1 mg
Purification
purified
Storage buffer
50mM tris HCl, pH 7.5, with 150mM NaCl, 0.1mM PMSF, 0.1mM EDTA, 0.25mM DTT, 25% glycerol, 10mM glutathione
Contains
no preservative
Storage conditions
-80°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Dry ice
Product Specific Information
For maximum recovery please spin prior to use. Unless noted below, aliquots of the 5 µg, 10 µg and 20 µg sizes of kinase are not recommended as materials can be used in original packaging until exhausted. For larger sizes, the number of freeze/thaws may be reduced by preparing aliquots, aliquots below 20 µL are not recommended. Please never store a kinase diluted. If properly stored at -80C, this product is guaranteed for 6 months from date of purchase.
This purified recombinant full-length protein can be used in a number of different applications, but it has been specifically validated for use with our Z'-LYTE™ assay technology to identify novel kinase inhibitors. NEK6 is also available in our SelectScreen™ Kinase Profiling Service.
• Validated for use with the Z'-LYTE assay technology
• Available in multiple pack sizes for convenient use
• Also available in our SelectSceen Kinase Profiling Service
Protein Form: Full Length, Recombinant, Active
The gene accession number for NEK6 is NP_055212.2.
Target Information
NEK6 kinase is a member of the NEK family. NEK6 is a serine/threonine kinase that controls the initiation of mitosis and is required for the metaphase-anaphase transition. The Aspergillus nidulans 'never in mitosis A' (NIMA) gene encodes a serine/threonine kinase that controls initiation of mitosis. NIMA-related kinases (NEKs) are a group of protein kinases that are homologous to NIMA. Evidence suggests that NEKs perform functions similar to those of NIMA. NEK6 encodes a NEK type protein kinase, which contains a C-terminal NIMA-like catalytic domain.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: NEK6; Never in mitosis A-related kinase 6; NIMA (never in mitosis gene a)-related kinase 6; NimA-related protein kinase 6; Protein kinase SID6-1512; putative serine-threonine protein kinase; RP11-101K10.6; Serine/threonine-protein kinase Nek6; SID; unnamed protein product
Gene Aliases: NEK6; SID6-1512
UniProt ID: (Human) Q9HC98
Entrez Gene ID: (Human) 10783
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