Gibco™

CTS™ OpTmizer™ Pro SFM, bottle format

Catalog number:  A4966101

Related applications:

Cell & Gene Therapy

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Description

Gibco CTS OpTmizer Pro SFM, no phenol red, is a novel serum-free medium (SFM) developed for the growth and expansion of human T lymphocytes (e.g., CD4+, CD8+, polyclonal, or antigen specific) used in allogeneic cell therapies. This medium improves central memory phenotype and cell growth by shifting the cell’s metabolism. The result is a larger population of central memory cells in a shorter period of time.

Benefits
• Maintains central memory T cells further into expansion and is well suited for longer workflows (>15 days)
• Offers >90% (average) T cell fold expansion (from healthy donors) compared to CTS OpTmizer medium
• Modest increases in central memory cells at early stage in expansion protocol result in larger cell yields at harvest
• Helps achieve the same number of cells in a shorter duration
• Ideally suited to the production of allogeneic therapies

Features
• Serum-free and xeno-free
• Supports high density cultures in static cultures
• New film (Aegis) and bag design (Cat. No. A4966101) allow compatibility with closed systems
• Supports T-cell activation using Dynabeads magnetic beads, soluble antibodies, and stimulatory antibody-presenting cell protocols

Increased efficiency and consistence performance
CTS OpTmizer Pro SFM, no phenol red, is serum-free and xeno-free and supports high density cultures in static cultures. It displays consistent performance in the support of T-cell expansion with better central memory phenotype in a shorter time.

Enhanced expansion
CTS OpTmizer Pro SFM, no phenol red, increases the number of central memory cells at an early stage in the expansion process and maintains T-cell functionality.

Simplify your transition into clinical research
The Gibco Cell Therapy Systems (CTS) brand offers a broad array of products for use in cell therapy applications, including media, reagents, growth factors, enzymes, cell selection/expansion reagents, and devices. CTS products deliver:
• Reduced burden in qualifying reagents
• Appropriate certificates of analysis and origin available
• Convenient access to our Drug Master File (DMF)

Specifications

Product Type: Cell Culture Media
Sterility: Sterile
Serum Level: Serum free, Xeno free
Shipping Condition: Room Temp
Tested For: Endotoxin
Volume (Metric): 1000 mL
Form: Liquid
Glutamine: No Glutamine
Phenol Red Indicator: No Phenol Red
Research Category: Cell Therapy
Shelf Life: 12 months
Reagent Type: Media
Cell Type: All types of T cells
Species: Human
State at Room Temperature: Yes
Solution Type: Media
With Additives: No Phenol red
Without Additives: Yes
Culture Type: Suspension
For Use With (Application): Cell Therapy, CAR-T, Allogeneic, T Cell Expansion Media, Cancer Immunotherapy