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Thermo Scientific Chemicals
tert-Butyl 2,2,2-trichloroacetimidate, 97%
CAS: 98946-18-0 | C6H10Cl3NO | 218.50 g/mol
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Catalog number B22039.06
also known as B22039-06
Price (EUR)
49,70
Each
Quantity:
5 g
Price (EUR)
49,70
Each
Chemical Identifiers
CAS98946-18-0
IUPAC Nametert-butyl 2,2,2-trichloroethanimidate
Molecular FormulaC6H10Cl3NO
InChI KeyCQXDYHPBXDZWBA-UHFFFAOYSA-N
SMILESCC(C)(C)OC(=N)C(Cl)(Cl)Cl
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Specifications
Specification Sheet
Specification SheetAppearance (Color)Clear colorless to pale yellow
FormLiquid
Assay (HPLC)≥96.0%
Identification (FTIR)Conforms
Refractive Index1.4535-1.4585 @ 20?C
tert-Butyl 2,2,2-trichloroacetimidate is used to produce di-tert-butyl peroxide at temperature of -5°C. It may be used in the synthesis of N-α-Fmoc-phospho(1-nitrophenylethyl-2-cyanoethyl)-L-serine, caged building block. It may be used in the conversion of alcohols and carboxylic acids to their respective ethers and esters.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
tert-Butyl 2,2,2-trichloroacetimidate is used to produce di-tert-butyl peroxide at temperature of -5°C. It may be used in the synthesis of N-α-Fmoc-phospho(1-nitrophenylethyl-2-cyanoethyl)-L-serine, caged building block. It may be used in the conversion of alcohols and carboxylic acids to their respective ethers and esters.
Solubility
Soluble in organic solvents, cyclo hexane.
Notes
Moisture sensitive. Store away from strong oxidizing agents, heat, water/ moisture.
tert-Butyl 2,2,2-trichloroacetimidate is used to produce di-tert-butyl peroxide at temperature of -5°C. It may be used in the synthesis of N-α-Fmoc-phospho(1-nitrophenylethyl-2-cyanoethyl)-L-serine, caged building block. It may be used in the conversion of alcohols and carboxylic acids to their respective ethers and esters.
Solubility
Soluble in organic solvents, cyclo hexane.
Notes
Moisture sensitive. Store away from strong oxidizing agents, heat, water/ moisture.
RUO – Research Use Only
General References:
- Deborah M Rothman; M Eugenio Vazquez; Elizabeth M Vogel; Barbara Imperiali. Caged phospho-amino acid building blocks for solid-phase peptide synthesis. Journal of Organic Chemistry. 2003, 68 (17), 5150-5154.
- Gary T. Wang; Sheldon Wang; Robert Gentles; Thomas Sowina; Clarence J. Maring; Dale J. Kempf; Warren M. Kati; Vincent Stoll;, Kent D. Stewart; Design, synthesis, and structural analysis of inhibitors of influenza neuraminidase containing a 2,3-disubstituted tetrahydrofuran-5-carboxylic acid core. Bioorganic & Medicinal Chemistry Letters. 2005, 15 (1-3), 125-128.
- Reagent for preparation of t-butyl ethers and esters under mild conditions: J. Chem. Soc., Perkin 1, 2247 (1985); Tetrahedron Lett., 29, 2483 (1988). See also Appendix 6.