Thermo Scientific Chemicals

Trimethylacetic anhydride, 99%, Thermo Scientific Chemicals

Catalog number: B22983.36
500 g, Each
Thermo Scientific Chemicals

Trimethylacetic anhydride, 99%, Thermo Scientific Chemicals

Catalog number: B22983.36
500 g, Each
Quantity
Catalog number: B22983.36
also known as B22983-36
Price (USD)
Quantity
-
Have Questions?

Chemical Identifiers

CAS
1538-75-6
IUPAC Name
2,2-dimethylpropanoyl 2,2-dimethylpropanoate
Molecular Formula
C10H18O3
InChI Key
PGZVFRAEAAXREB-UHFFFAOYSA-N
SMILES
CC(C)(C)C(=O)OC(=O)C(C)(C)C
Appearance (Color)
Clear colorless
Form
Liquid
Assay (GC)
≥98.5%
Identification (FTIR)
Conforms
Refractive Index
1.4075-1.4105 @ 20?C

Description

Trimethylacetic anhydride is used as acylation and esterification reagents. It is involved in acylation and esterification reactions with anilines and phenols. It is also used in solid-phase oligonucleotide synthesis and in the kinetic resolution of racemic 2-hydroxy-gamma-butyrolactones with diphenylacetic acid. It is also employed in the production of cyano-4, N-tert-butyloxycarbonyl piperidine.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Trimethylacetic anhydride is used as acylation and esterification reagents. It is involved in acylation and esterification reactions with anilines and phenols. It is also used in solid-phase oligonucleotide synthesis and in the kinetic resolution of racemic 2-hydroxy-gamma-butyrolactones with diphenylacetic acid. It is also employed in the production of cyano-4, N-tert-butyloxycarbonyl piperidine.

Solubility
Miscible with acetonitrile.

Notes
Moisture sensitive. Incompatible with strong oxidizing agents, strong acids, strong bases and strong reducing agents.
RUO – Research Use Only

Figures

Documents & Downloads

Certificates

    Frequently asked questions (FAQs)

    Citations & References

    Search citations by name, author, journal title or abstract text