Congo Red, indicator grade

Name: Congo Red, indicator grade
SKU: B24310.22

CAS: 573-58-0 | C32H22N6Na2O6S2 | 696.664 g/mol

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Catalog number B24310.22

also known as B24310-22

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Quantity:

100 g

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Chemical Identifiers

CAS573-58-0

IUPAC Namedisodium 4-amino-3-(2-{4'-[2-(1-amino-4-sulfonatonaphthalen-2-yl)diazen-1-yl]-[1,1'-biphenyl]-4-yl}diazen-1-yl)naphthalene-1-sulfonate

Molecular FormulaC32H22N6Na2O6S2

InChI KeyIQFVPQOLBLOTPF-UHFFFAOYSA-L

SMILES[Na+].[Na+].NC1=C2C=CC=CC2=C(C=C1N=NC1=CC=C(C=C1)C1=CC=C(C=C1)N=NC1=CC(=C2C=CC=CC2=C1N)S([O-])(=O)=O)S([O-])(=O)=O

Specifications

Specification Sheet

FormPowder

Specific Absorbance (E 1%/1cm)>500 @ lambda-max (pH 7)

Loss on Drying≤5.0%

Solution Test0.1% in water: clear

lambda-max (UV-Vis)490-500nm @ pH 7

Congo red is useful for staining and visual detection of amyloid deposits. It inhibits the accumulation of the scrapie-associated, protease-resistant isoform of protein PrP without affecting the metabolism of the normal isoform.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Congo red is useful for staining and visual detection of amyloid deposits. It inhibits the accumulation of the scrapie-associated, protease-resistant isoform of protein PrP without affecting the metabolism of the normal isoform.

Solubility
Soluble in water 25 g/L.

Notes
Store away from oxidizing agents, acids, reducing agents.

RUO – Research Use Only

General References:

Young Hye Kim; Se Hoon Choi; Carla D'Avanzo; Matthias Hebisch; Christopher Sliwinski; Enjana Bylykbashi; Kevin J Washicosky; Justin B Klee; Oliver Brüstle; Rudolph E Tanzi; Doo Yeon Kim. A 3D human neural cell culture system for modeling Alzheimer's disease. Nature Protocols. 2015, 10 (7), 985-1006.
D P Penney; J M Powers; M Frank; C Willis; C Churukian. Analysis and testing of biological stains--the Biological Stain Commission Procedures. Biotechnic and Histochemistry. 2002, 77 (5-6), 237-275.